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  1. Journal of Mechanical Science and Technology
  2. Journal of Mechanical Science and Technology : Volume 30
  3. Journal of Mechanical Science and Technology : Volume 30, Issue 9, September 2016
  4. Study on drug powder acceleration in a micro shock tube
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Journal of Mechanical Science and Technology : Volume 31
Journal of Mechanical Science and Technology : Volume 30
Journal of Mechanical Science and Technology : Volume 30, Issue 12, December 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 11, November 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 10, October 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 9, September 2016
Experimental study of bubbly swirling flow in a vertical tube using ultrasonic velocity profiler (UVP) and wire mesh sensor (WMS)
Effect of surface conditions on blast wave propagation
High-efficiency design optimization of a centrifugal pump
Direct numerical simulation of 3D particle motion in an evaporating liquid film
Pressure waves in bubbly liquids
High frequency travelling surface acoustic waves for microparticle separation
Optimal design of impeller for centrifugal compressor under the influence of one-way fluid-structure interaction
Aerodynamic load maps of bluff bodies: Measurement and diagnostics
An efficient shock-capturing scheme for simulating compressible homogeneous mixture flow
Analysis of high-speed train flow structures under crosswind
Flow analysis in a return channel of a multi-stage centrifugal pump
Optimization study on pin tip diameter of an impact-pin nozzle at high pressure ratio
Study on drug powder acceleration in a micro shock tube
A bidirectional valveless piezoelectric micropump with three chambers applying synthetic jet
Determination of the road load on electric two-wheelers using the torque-current relationship of the drive motor
Dynamic characteristics of rotating pretwisted clamped-clamped beam under thermal stress
Dynamic simulation and analysis of the elevating mechanism of a forklift based on a power bond graph
Vibrational energy flow analysis of coupled cylindrical thin shell structures
A comparative study of finite element methodologies for the prediction of torsional response of bladed rotors
A control strategy for electro-magneto-mechanical system based on virtual system model
Two-dimensional dynamic analysis of sandwich plates with gradient foam cores
Simultaneous identification of bearing dynamic coefficients in a water-gas lubricated hydrostatic spindle with a big thrust disc
A vibration model for fault diagnosis of planetary gearboxes with localized planet bearing defects
Improved three-variable element-free Galerkin method for vibration analysis of beam-column models
Parametric study on nonlinear vibration of composite truss core sandwich plate with internal resonance
Prediction of the vibration characteristics for wheeled tractor with suspended driver seat including air spring and MR damper
The time-delay coupling nonlinear effect in sky-hook control of vibration isolation systems using Magneto-Rheological Fluid dampers
Dynamic analysis of Timoshenko beam subjected to support motions
Vibration analysis of rotating cantilever beams orienting inward
Quadratic temporal finite element method for linear elastic structural dynamics based on mixed convolved action
Multi-objective optimization of powder mixed electric discharge machining parameters for fabrication of biocompatible layer on β-Ti alloy using NSGA-II coupled with Taguchi based response surface methodology
Nondestructive evaluation algorithm of fatigue cracks and far-side corrosion around a rivet fastener in multi-layered structures
Prediction of fracture parameters of circumferential through-wall cracks in the interface between an elbow and a pipe under internal pressure
Wake vortex interaction effects on energy extraction performance of tandem oscillating hydrofoils
Numerical simulation of fluid flow and forced convection heat transfer around a circular cylinder with control rods located in equilateral triangular arrangement
Prediction of air-oil interface location in tied-shaft type fluid dynamic bearings
Effects of anisotropic properties on bursting behavior of rectangular cup with a V-notch
Finite element investigation of the biomechanical responses of human foot to the heel height and a rigid hemisphere cleat
Performance evaluation on vacuum pumps using nanolubricants
Dielectric oil-based polymer actuator for improved thickness strain and breakdown voltage
Performance of leaf springs made of composite material subjected to low frequency impact loading
Investigation of mechanical properties of bimetallic square tubes produced by shape rolling of Al/Cu circular pipes
Numerical analysis of variable polarity arc weld pool
Die design of large spherical curvature hot forming process for improving the dimensional accuracy
Design optimization of 3PRS parallel manipulator using global performance indices
Design, modeling and optimization of an underwater manipulator with four-bar mechanism and compliant linkage
Mobility analysis for parallel manipulators based on intersection of screw manifolds
Finite time SDRE control design for mobile robots with differential wheels
Thermal interaction of a circular plate-ring structure using digital image correlation technique and infrared heating system
Design of combustion bowl geometry to meet final Tier 4 of 11 L non-road heavy-duty diesel engine with multi-dimensional combustion simulation
Numerical analysis on the effect of voltage change on removing condensed water inside the GDL of a PEM fuel cell
Local electrochemical characteristics at various operating pressure and temperature values using a segmented polymer electrolyte membrane fuel cell
Journal of Mechanical Science and Technology : Volume 30, Issue 8, August 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 7, July 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 6, June 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 5, May 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 4, April 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 3, March 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 2, February 2016
Journal of Mechanical Science and Technology : Volume 30, Issue 1, January 2016
Journal of Mechanical Science and Technology : Volume 29
Journal of Mechanical Science and Technology : Volume 28
Journal of Mechanical Science and Technology : Volume 27
Journal of Mechanical Science and Technology : Volume 26
Journal of Mechanical Science and Technology : Volume 25
Journal of Mechanical Science and Technology : Volume 24
Journal of Mechanical Science and Technology : Volume 23
Journal of Mechanical Science and Technology : Volume 22
Journal of Mechanical Science and Technology : Volume 21
Journal of Mechanical Science and Technology : Volume 20
Journal of Mechanical Science and Technology : Volume 19
Journal of Mechanical Science and Technology : Volume 18
Journal of Mechanical Science and Technology : Volume 17
Journal of Mechanical Science and Technology : Volume 16
Journal of Mechanical Science and Technology : Volume 15
Journal of Mechanical Science and Technology : Volume 14
Journal of Mechanical Science and Technology : Volume 13
Journal of Mechanical Science and Technology : Volume 12
Journal of Mechanical Science and Technology : Volume 11

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Study on drug powder acceleration in a micro shock tube

Content Provider SpringerLink
Author Zhang, Guang Jin, Ying Zi Setoguchi, Toshiaki Kim, Heuy Dong
Copyright Year 2016
Abstract Recently, micro shock tubes have been widely used in the medical engineering. The needle-free drug delivery device which mainly consists of a micro shock tube and an expanded nozzle has been produced to inject drug powders into human and animal bodies without any sharp metal needles. The drug powders were delivered by obtaining high momentum, which can be done by accelerating drug powders in the micro shock tube and supersonic nozzle. The particle-gas flows are induced by the incident shock wave developing by rupturing the diaphragm in the micro shock tube and again accelerated in the supersonic nozzle. The momentum of injected drug particles should be strictly controlled otherwise patients will suffer from skin injury or hurt. Even though micro shock tubes have been investigated in the past several decades, the detailed studies on particle-gas flows in the micro shock tube were rare to date due to the micro size and difficult experimental operation on micro shock tubes. In this paper, the experimental and numerical studies were carried out on investigating particle-gas flows in a designed micro shock tube. Particle tracking velocimetry (PTV) was performed to calculated particle average velocity at the exit of the supersonic nozzle. The nozzle flows were analyzed by obtaining instantaneous particle fields. The particle number density ratio was also investigated in the test section. The numerical simulations were performed by calculating unsteady Naver-Stokes equations on compressible flows and using fully implicit finite volume schemes. Discrete phase model (DPM) was used for simulating particle-gas flows in the micro shock tube. Particle diameter and density were varied to investigate their effects on the particle-gas flows. Unsteady particle-gas flows and shock wave propagation were obtained in details in the micro shock tube for present experimental and numerical studies.
Starting Page 4007
Ending Page 4013
Page Count 7
File Format PDF
ISSN 1738494X
Journal Journal of Mechanical Science and Technology
Volume Number 30
Issue Number 9
e-ISSN 19763824
Language English
Publisher Korean Society of Mechanical Engineers
Publisher Date 2016-09-22
Publisher Place Seoul
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Micro shock tube Particle-gas flows Particle velocity PTV Numerical simulation Mechanical Engineering Vibration, Dynamical Systems, Control Industrial and Production Engineering
Content Type Text
Resource Type Article
Subject Mechanics of Materials Mechanical Engineering
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