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  1. Medical and Biological Engineering and Computing
  2. Medical and Biological Engineering and Computing : Volume 37
  3. Medical and Biological Engineering and Computing : Volume 37, Issue 1, January 1999
  4. Microstructures for studies of cultured neural networks
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Medical and Biological Engineering and Computing : Volume 55
Medical and Biological Engineering and Computing : Volume 54
Medical and Biological Engineering and Computing : Volume 53
Medical and Biological Engineering and Computing : Volume 52
Medical and Biological Engineering and Computing : Volume 51
Medical and Biological Engineering and Computing : Volume 50
Medical and Biological Engineering and Computing : Volume 49
Medical and Biological Engineering and Computing : Volume 48
Medical and Biological Engineering and Computing : Volume 47
Medical and Biological Engineering and Computing : Volume 46
Medical and Biological Engineering and Computing : Volume 45
Medical and Biological Engineering and Computing : Volume 44
Medical and Biological Engineering and Computing : Volume 43
Medical and Biological Engineering and Computing : Volume 42
Medical and Biological Engineering and Computing : Volume 41
Medical and Biological Engineering and Computing : Volume 40
Medical and Biological Engineering and Computing : Volume 39
Medical and Biological Engineering and Computing : Volume 38
Medical and Biological Engineering and Computing : Volume 37
Medical and Biological Engineering and Computing : Volume 37, Issue 6, November 1999
Medical and Biological Engineering and Computing : Volume 37, Issue 5, September 1999
Medical and Biological Engineering and Computing : Volume 37, Issue 4, July 1999
Medical and Biological Engineering and Computing : Volume 37, Issue 3, May 1999
Medical and Biological Engineering and Computing : Volume 37, Issue 2, March 1999
Medical and Biological Engineering and Computing : Volume 37, Issue 1, January 1999
Editorial: Your paper has been accepted
Multichannel magnetocardiographic measurements with a physical thorax phantom
Technique of distortion correction in endoscopic images using a polynomial expansion
Application of dynamic computed tomography for measurements of local aortic elastic modulus
A method for determining the information capacity of x-ray imaging scintillator detectors by means of luminescence and modulation transfer function measurements
Measurement of forces associated with compression therapy
Gait control system for functional electrical stimulation using neural networks
Estimation of respiratory volumes from the photoplethysmographic signal. Part I: experimental results
Estimation of respiratory volumes from the photoplethysmographic signal. Part 2: a model study
Verylow frequency variability in arterial blood pressure and blood volume pulse
Computer modelling of the cerebrospinal fluid flow dynamics of aqueduct stenosis
Study of catheter designs and drug mixing processes using 2D steady numerical simulations
QT interval analysis on ambulatory electrocardiogram recordings: a selective beat averaging approach
Blind separation of multichannel electrogastrograms using independent component analysis based on a neural network
Artefact cancellation in motor-sensory evoked potentials: two approaches using adaptive filtration and exponential approximation
Temporal and spatial complexity measures for electroencephalogram based brain-computer interfacing
A fast recursive-least-squares adaptive notch filter and its applications to biomedical signals
Computerised volumetric analysis of lesions in multiple sclerosis using new semi-automatic segmentation software
Dependence of cardiac strength-interval curves on pacing rate
Microstructures for studies of cultured neural networks
Computer modelling of the adsorption of proteins on solid surfaces under the influence of double layer and van der waals energy
Amphiphile-induced spherical microexovesicle corresponds to an extreme local area difference between two monolayers of the membrane bilayer
N,N-dicarboxymethyl chitosan as delivery agent for bone morphogenetic protein in the repair of articular cartilage
Medical and Biological Engineering and Computing : Volume 36
Medical and Biological Engineering and Computing : Volume 35

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Microstructures for studies of cultured neural networks

Content Provider SpringerLink
Author Maher, M. P. Dvorak Carbone, H. Pine, J. Wright, J. A. Tai, Y. C.
Copyright Year 1999
Abstract A description is given of a functional silicon micromachined device that permits non-invasive, bidirectional, highly specific communication with cultured mammalian neurons. The heart of the system is a well structure that holds the cell in close proximity to a metal extracellular electrode while permitting normal outgrowth of axons and dendrites. An iterative approach is used to create a design that allows normal growth of the neurons while preventing their escape. An array of 16 such neurowells makes it possible to perform studies of biological neural network development and function with unprecedented detail.
Starting Page 110
Ending Page 118
Page Count 9
File Format PDF
ISSN 01400118
Journal Medical and Biological Engineering and Computing
Volume Number 37
Issue Number 1
e-ISSN 17410444
Language English
Publisher Kluwer Academic Publishers
Publisher Date 1999-01-01
Publisher Place Dordrecht
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Neurochip Multielectrode arrays Extracellular recording Hippocampal neurons Dissociated cell culture Biomedical Engineering Human Physiology Imaging Radiology Computer Applications
Content Type Text
Resource Type Article
Subject Biomedical Engineering Computer Science Applications
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