NDLI: Patterns of variability at the major histocompatibility class I and class II loci in populations of the endangered cyprinid Ladigesocypris ghigii

Content Provider	SpringerLink
Author	Moutou, Katerina A. Mamuris, Zissis Firme, Tania Kontou, Maria Sarafidou, Theologia Stoumboudi, Maria Th.
Copyright Year	2011
Abstract	The patterns of MHC diversity were studied at UAA and DAB1 loci and the two domains involved in the recognition of antigenic peptides (α2 and β1, respectively) in eight Ladigesocypris ghigii populations inhabiting streams and a concrete reservoir, in order to understand the significance of these genes in bottlenecked populations of an endemic species and develop conservation rationale. In agreement with previous study employing RAPD and mtDNA markers (Mamuris et al., Freshw Biol 50:1441–1453, 2005), both loci exhibited a very low level of polymorphism with only two and four alleles detected for UAA and DAB1, respectively. The functional MHC diversity was even lower since UAA alleles were distinguished by a single synonymous substitution. The type of habitat did not affect the level of polymorphism. Our data suggest that DAB1 polymorphism might be the outcome of the positive selection, imposed by the temporal and spatial variation of pathogen load, and the genetic drift as a result of successive habitat shrinkage and deterioration by water abstraction year after year. The populations studied were significantly less diverged at MHC loci than expected based on nuclear and mtDNA markers, suggesting that common parasites might act as causative factors to homogenize selection. Sufficient epidemiological data are required for the interpretation of the results and decision-making on suitable conservation actions.
Starting Page	1159
Ending Page	1171
Page Count	13
File Format	PDF
ISSN	15660621
Journal	Conservation Genetics
Volume Number	12
Issue Number	5
e-ISSN	15729737
Language	English
Publisher	Springer Netherlands
Publisher Date	2011-05-03
Publisher Place	Dordrecht
Access Restriction	Subscribed
Subject Keyword	Ladigesocypris ghigii MHC diversity UAA DAB1 Conservation Animal Anatomy / Morphology / Histology Evolutionary Biology Conservation Biology/Ecology Plant Sciences
Content Type	Text
Resource Type	Article
Subject	Ecology, Evolution, Behavior and Systematics Genetics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Libarray of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

MHC diversity in bottlenecked populations: a simulation model

Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla)

Primers for the amplification of major histocompatibility complex class I and II loci in the recovering red-crowned parakeet

Characterisation of major histocompatibility complex class II alleles in the natterjack toad, Bufo calamita

MHC screening for marsupial conservation: extremely low levels of class II diversity indicate population vulnerability for an endangered Australian marsupial

Rapid identification of major histocompatibility complex class I haplotypes using deep sequencing in an endangered Old World monkey

Allelic diversity and patterns of selection at the major histocompatibility complex class I and II loci in a threatened shorebird, the Snowy Plover (Charadrius nivosus).

Depleted genetic variation of the European ground squirrel in Central Europe in both microsatellites and the major histocompatibility complex gene: implications for conservation

Primers for amplifying major histocompatibility complex class II DQB and DRB exon 2 in the Australian sea lion (Neophoca cinerea)

Patterns of variability at the major histocompatibility class I and class II loci in populations of the endangered cyprinid Ladigesocypris ghigii

Similar Documents

MHC diversity in bottlenecked populations: a simulation model

Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla)

Primers for the amplification of major histocompatibility complex class I and II loci in the recovering red-crowned parakeet

Characterisation of major histocompatibility complex class II alleles in the natterjack toad, Bufo calamita

MHC screening for marsupial conservation: extremely low levels of class II diversity indicate population vulnerability for an endangered Australian marsupial

Rapid identification of major histocompatibility complex class I haplotypes using deep sequencing in an endangered Old World monkey

Allelic diversity and patterns of selection at the major histocompatibility complex class I and II loci in a threatened shorebird, the Snowy Plover (Charadrius nivosus).

Depleted genetic variation of the European ground squirrel in Central Europe in both microsatellites and the major histocompatibility complex gene: implications for conservation

Primers for amplifying major histocompatibility complex class II DQB and DRB exon 2 in the Australian sea lion (Neophoca cinerea)

Patterns of variability at the major histocompatibility class I and class II loci in populations of the endangered cyprinid Ladigesocypris ghigii