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  1. Monatshefte für Chemie - Chemical Monthly
  2. Monatshefte für Chemie - Chemical Monthly : Volume 147
  3. Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 1, January 2016
  4. Electrochemical oxidation of zopiclone
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Monatshefte für Chemie - Chemical Monthly : Volume 148
Monatshefte für Chemie - Chemical Monthly : Volume 147
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 12, December 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 11, November 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 10, October 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 9, September 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 8, August 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 7, July 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 6, June 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 5, May 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 4, April 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 3, March 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 2, February 2016
Monatshefte für Chemie - Chemical Monthly : Volume 147, Issue 1, January 2016
Conference XXXVth Modern Electrochemical Methods, Czech Republic, 2015
Electrochemical behavior of 7-deazaguanine- and 7-deazaadenine-modified DNA at the hanging mercury drop electrode
Interactions of fluorescent dye SYBR Green I with natural and 7-deazaguanine-modified DNA studied by fluorescence and electrochemical methods
Factors influencing voltammetric reduction of 5-nitroquinoline at boron-doped diamond electrodes
Electrochemical properties of α-tocopherol in aqueous electrolytes after its previous extraction into the glassy carbon paste from aqueous-acetonic mixture
Determination of illicit drugs and their metabolites contamination on banknotes
Formation and investigation of 6-cysteinyl amino methylated β-cyclodextrin self-assembled monolayers
Electrochemical oxidation of zopiclone
A simple and easy way to enhance sensitivity of Sn(IV) on bismuth film electrodes with the use of a mediator
Verification of antibody labelling efficiency as an important step in ELISA/QLISA development
Electrochemical oxidative dimerization of monobrominated phenols and pentabromophenol in methanol-aqueous media
Voltammetric determination of homovanillic acid and vanillylmandelic acid on a disposable electrochemical measuring cell system with integrated carbon composite film electrodes
Occurrence of pharmaceuticals, illicit drugs, and resistant types of bacteria in hospital effluent and their effective degradation by boron-doped diamond electrodes
Electrochemical and spectral behaviour of miR-34a-5p
Differential pulse voltammetric determination of 4-nitroaniline using a glassy carbon electrode: comparative study between cathodic and anodic quantification
Interaction study of methyl violet 2B with DNA and voltammetric determination of DNA in aqueous solutions
Voltammetry of benzodiazepines on meniscus-modified silver solid amalgam electrode
Voltammetric determination of fenitrothion and study of its interaction with DNA at a mercury meniscus modified silver solid amalgam electrode
Polarographic and voltammetric determination of genotoxic 4-nitroindane at mercury electrodes
Electrochemical study of 5-nitroquinoline using carbon film electrode and its determination in model samples of drinking and river water
Automotive industry wastewater treatment by mixture of enzymes
Voltammetric detection of phytochelatin transported across unmodified and protoplast modified model phospholipid membranes
Determination of 2-nitrophenol using carbon film electrode
Application of silver solid amalgam electrode for determination of formamidine amitraz
Surfactant/carbon nanofibers-modified electrode for the determination of vanillin
Enhanced hydrogen bioproduction from bird-cherry leaves using enzyme mixture
Sensitive voltammetric determination of herbicide terbutryn using solid electrodes based on silver amalgam and boron-doped diamond
Sensitive voltammetric method for determination of herbicide metribuzin using silver solid amalgam electrode
Voltammetric determination of antioxidant 4,4′-methylenebis(2,6-di-tert-butylphenol) in lubricating oils using gold disc electrode
Prevalence, dynamics, and biochemical predictors of optic nerve remyelination after methanol-induced acute optic neuropathy: a 2-year prospective study in 54 patients
Factors predicting optic nerve axonal degeneration after methanol-induced acute optic neuropathy: a 2-year prospective study in 54 patients
Monatshefte für Chemie - Chemical Monthly : Volume 146
Monatshefte für Chemie - Chemical Monthly : Volume 145
Monatshefte für Chemie - Chemical Monthly : Volume 144
Monatshefte für Chemie - Chemical Monthly : Volume 143
Monatshefte für Chemie - Chemical Monthly : Volume 142
Monatshefte für Chemie - Chemical Monthly : Volume 141
Monatshefte für Chemie - Chemical Monthly : Volume 140
Monatshefte für Chemie - Chemical Monthly : Volume 139
Monatshefte für Chemie - Chemical Monthly : Volume 138
Monatshefte für Chemie - Chemical Monthly : Volume 137
Monatshefte für Chemie - Chemical Monthly : Volume 136
Monatshefte für Chemie - Chemical Monthly : Volume 135
Monatshefte für Chemie - Chemical Monthly : Volume 134
Monatshefte für Chemie - Chemical Monthly : Volume 133
Monatshefte für Chemie - Chemical Monthly : Volume 132
Monatshefte für Chemie - Chemical Monthly : Volume 131
Monatshefte für Chemie - Chemical Monthly : Volume 130
Monatshefte für Chemie - Chemical Monthly : Volume 129
Monatshefte für Chemie - Chemical Monthly : Volume 128

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Electrochemical oxidation of zopiclone

Content Provider SpringerLink
Author Táborský, Jakub Švidrch, Martin Kurka, Ondřej Borovcová, Lucie Bednář, Petr Barták, Petr Skopalová, Jana
Copyright Year 2015
Abstract Electrochemical behaviour of zopiclone was investigated on glassy carbon electrode in static and rotation disc arrangement. Strong influence of kinetics and adsorption phenomena on the electrode processes was proved by voltammetric techniques. Controlled potential electrolysis in off-line and on-line combination with tandem mass spectrometry was employed for investigation of the products of electrochemical oxidation. N-Desmethyl zopiclone was identified and three other oxidation products formed by an introduction of one or two oxygen atom(s) to the molecule of zopiclone (including zopiclone N-oxide) were characterized. Based on mass spectrometric investigation of those products, piperazine moiety was proved as a target of electrochemical oxidation of zopiclone. Since N-desmethyl zopiclone and zopiclone N-oxide have been reported as products of enzymatic metabolism of the drug, the combination of electrochemistry with mass spectrometry may be considered as a reliable tool for simulation of some metabolic transformations.
Starting Page 53
Ending Page 60
Page Count 8
File Format PDF
ISSN 00269247
Journal Monatshefte für Chemie - Chemical Monthly
Volume Number 147
Issue Number 1
e-ISSN 14344475
Language English
Publisher Springer Vienna
Publisher Date 2015-12-07
Publisher Place Vienna
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Electrochemistry Mass spectroscopy Voltammetry N -Desmethyl zopiclone Chemistry/Food Science Organic Chemistry Inorganic Chemistry Analytical Chemistry Physical Chemistry Theoretical and Computational Chemistry
Content Type Text
Resource Type Article
Subject Chemistry
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