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  1. Bulletin of Environmental Contamination and Toxicology
  2. Bulletin of Environmental Contamination and Toxicology : Volume 89
  3. Bulletin of Environmental Contamination and Toxicology : Volume 89, Issue 4, October 2012
  4. Lead Bone Toxicity in Growing Rats Exposed to Chronic Intermittent Hypoxia
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Bulletin of Environmental Contamination and Toxicology : Volume 97
Bulletin of Environmental Contamination and Toxicology : Volume 96
Bulletin of Environmental Contamination and Toxicology : Volume 95
Bulletin of Environmental Contamination and Toxicology : Volume 94
Bulletin of Environmental Contamination and Toxicology : Volume 93
Bulletin of Environmental Contamination and Toxicology : Volume 92
Bulletin of Environmental Contamination and Toxicology : Volume 91
Bulletin of Environmental Contamination and Toxicology : Volume 90
Bulletin of Environmental Contamination and Toxicology : Volume 89
Bulletin of Environmental Contamination and Toxicology : Volume 89, Issue 6, December 2012
Bulletin of Environmental Contamination and Toxicology : Volume 89, Issue 5, November 2012
Bulletin of Environmental Contamination and Toxicology : Volume 89, Issue 4, October 2012
Lead Bone Toxicity in Growing Rats Exposed to Chronic Intermittent Hypoxia
Effect of Sulfhydryl Modification on Rat Kidney Basolateral Plasma Membrane Transport Function
Stress-Response Protein Expression and DAF-16 Translocation were Induced in Tributyltin-Exposed Caenorhabditis elegans
Hematopathology in Sprague–Dawley Rats Following Sub-Chronic Topical Application of Para-Phenylenediamine
Sodium Sulfite Enhances Rhinovirus-Induced Chemokine Production in Airway Epithelial Cells
Effects of Paclobutrazol Exposure on Antioxidant Defense System in Sebastiscus marmoratus
Growth Study and Hydrocarbonoclastic Potential of Microorganisms Isolated from Aviation Fuel Spill Site in Ibeno, Nigeria
Fast Genomic Biomarker Responses of Retene and Pyrene in Liver of Juvenile Rainbow Trout, Oncorhynchus mykiss
An Improved AhR Reporter Gene Assay for Analyzing Dioxins in Soil, Sediment and Fish
Development and Validation of an Analytical Method to Determine Fipronil and its Degradation Products in Soil Samples
Copper Losses in Surface Runoff from Flatwoods Citrus Production Areas
Total Mercury in Yellow Knights (Tricholoma equestre) Mushrooms and Beneath Soils
Mercury Bio-Concentration by Puffballs (Lycoperdon perlatum) and Evaluation of Dietary Intake Risks
Chemical Speciation of Metals in Surface Sediments from Small Urban and Agricultural Rivers
Distribution of Metals in Surface Sediments from a Small River Flowing Through Urban and Agricultural Areas
Concentration and Spatial Distribution of Lead in Soil Used for Ammunition Destruction
Cadmium and Lead Levels Along the Estuarine Ecosystem of Tigre River-San Andres Lagoon, Tamaulipas, Mexico
Pugilina morio L., a New Imposex Exhibitor from South American Estuarine Environments: Approach for a Non-Lethal Method to Evaluate Imposex
Appraisal of Heavy Metals in Groundwater in Chennai City Using a HPI Model
Bioaccumulation and Distribution of Metals in Sediments and Avicenna marina Tissues in the Hara Biosphere Reserve, Iran
Biomonitoring of Metals in Ganga Water at Different Ghats of Haridwar: Implications of Constructed Wetland for Sewage Detoxification
Residues of Organochlorine Pesticides in Water and Suspended Particulate Matter from Xiangshan Bay, East China Sea
Chemical and Bioassay Analysis of Estrogen Pollution in the Surface Water of the Tiaoxi River, the Source River for Taihu Lake
Cadmium and Lead Concentrations in the Fish Tissues of a Coastal Lagoon System of the SE Gulf of California
Effect of Bauxite Mineralized Soil on Residual Metal Levels in Some Post Harvest Food Crops in Jamaica
Contamination of Metals in Tissues of Ctenopharyngodon idella and Perca fluviatilis, from Anzali Wetland, Iran
Mercury Concentrations in Muscle and Liver Tissue of Fish from Marshes Along the Magdalena River, Colombia
Mercury in Different Feather Types from Great Cormorants (Phalacrocorax carbo L.) Inhabiting the Vistula Lagoon Ecosystem in Poland
Determination of Cyantraniliprole and its Major Metabolite Residues in Pakchoi and Soil Using Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry
Determination and Dynamics of Ethylicin Residues in Cotton-Field Ecosystem
Investigation of Fluoroquinolones, Sulfonamides and Macrolides in Long-Term Wastewater Irrigation Soil in Tianjin, China
Residue Dynamics of Spirotetramat and Imidacloprid in/on Mango and Soil
Comparison of Greenhouse and Field Degradation Behaviour of Isoprocarb, Hexaflumuron and Difenoconazole in Perilla frutescens
Dissipation of Penconazole in Tomatoes and Soil
Iprodione Residues and Dissipation Rates in Tobacco Leaves and Soil
Organochlorine Pesticide Residues in Bovine Milk from Organic Farms in Chiapas, Mexico
Application of Solid-Phase Microextraction Method to Determine Bioavailable Fraction of PAH in Hazardous Waste
Effect of Titanium Dioxide Nanoparticles on Gamma-Ray Treatment of Phenol in Different Matrices: Implications in Toxicity Toward Daphnia magna
Assessment of Fine Particulate Matter and Gaseous Pollutants in Workplace Atmosphere of Metallic Industry
Effects of Environmental Factors on the Uptake Rates of Dissolved Nitrogen by a Salt-water Green Alga (Oocystis borgei Snow)
Red Fox (Vulpes vulpes Linnaeus, 1758) as Biological Indicator for Environmental Pollution in Hungary
Evaluation of the Sensitivity of Freshwater Organisms Used in Toxicity Tests of Wastewater from Explosives Company
Oral Toxicity of Fipronil Insecticide Against the Stingless Bee Melipona scutellaris (Latreille, 1811)
Assessment of the Levels of Polybrominated Diphenyl Ethers in Blood Samples from Guadalajara, Jalisco, Mexico
Bulletin of Environmental Contamination and Toxicology : Volume 89, Issue 3, September 2012
Bulletin of Environmental Contamination and Toxicology : Volume 89, Issue 2, August 2012
Bulletin of Environmental Contamination and Toxicology : Volume 89, Issue 1, July 2012
Bulletin of Environmental Contamination and Toxicology : Volume 88
Bulletin of Environmental Contamination and Toxicology : Volume 87
Bulletin of Environmental Contamination and Toxicology : Volume 86
Bulletin of Environmental Contamination and Toxicology : Volume 85
Bulletin of Environmental Contamination and Toxicology : Volume 84
Bulletin of Environmental Contamination and Toxicology : Volume 83
Bulletin of Environmental Contamination and Toxicology : Volume 82
Bulletin of Environmental Contamination and Toxicology : Volume 81
Bulletin of Environmental Contamination and Toxicology : Volume 80
Bulletin of Environmental Contamination and Toxicology : Volume 79
Bulletin of Environmental Contamination and Toxicology : Volume 78
Bulletin of Environmental Contamination and Toxicology : Volume 77
Bulletin of Environmental Contamination and Toxicology : Volume 76
Bulletin of Environmental Contamination and Toxicology : Volume 75
Bulletin of Environmental Contamination and Toxicology : Volume 74
Bulletin of Environmental Contamination and Toxicology : Volume 73
Bulletin of Environmental Contamination and Toxicology : Volume 72
Bulletin of Environmental Contamination and Toxicology : Volume 71
Bulletin of Environmental Contamination and Toxicology : Volume 70
Bulletin of Environmental Contamination and Toxicology : Volume 69
Bulletin of Environmental Contamination and Toxicology : Volume 68
Bulletin of Environmental Contamination and Toxicology : Volume 67
Bulletin of Environmental Contamination and Toxicology : Volume 66
Bulletin of Environmental Contamination and Toxicology : Volume 65
Bulletin of Environmental Contamination and Toxicology : Volume 64
Bulletin of Environmental Contamination and Toxicology : Volume 63
Bulletin of Environmental Contamination and Toxicology : Volume 62
Bulletin of Environmental Contamination and Toxicology : Volume 61
Bulletin of Environmental Contamination and Toxicology : Volume 60
Bulletin of Environmental Contamination and Toxicology : Volume 59
Bulletin of Environmental Contamination and Toxicology : Volume 58

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Lead Bone Toxicity in Growing Rats Exposed to Chronic Intermittent Hypoxia

Content Provider SpringerLink
Author Conti, María I. Bozzini, Clarisa Facorro, Graciela B. Lee, Ching M. Mandalunis, Patricia M. Piehl, Lidia L. Piñeiro, Adriana E. Terrizzi, Antonela R. Martínez, María P.
Copyright Year 2012
Abstract Lead chronic intoxication under hypoxic conditions revealed growth retardation in growing rats and damages on femoral and mandibular bones that predispose to fractures. These findings aimed us to investigate if bone material and geometric properties, bone mass in terms of histomorphometry or antioxidant capacity are also impaired in such experimental model. Combined treatments significantly reduced hemimandible cross sectional geometry and intrinsic stiffness (−16 % and −34 %); tibia and hemimandible bone volume (−45 % and −40 %) and growth plate cartilage thickness (−19 %). These results show a previously unreported toxic effect of lead on mandible however, longer studies should be necessary to evaluate if an adaptation of bone architecture to maintain structural properties may occur and if the oxidative stress can be identified as the primary contributory agent in the pathogenesis of lead poisoning.
Starting Page 693
Ending Page 698
Page Count 6
File Format PDF
ISSN 00074861
Journal Bulletin of Environmental Contamination and Toxicology
Volume Number 89
Issue Number 4
e-ISSN 14320800
Language English
Publisher Springer-Verlag
Publisher Date 2012-07-31
Publisher Place New York
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Lead poisoning Intermittent hypoxia Bone biomechanics Bone histomorphometry Oxidative stress Environmental Chemistry Ecotoxicology Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution Environmental Health Soil Science & Conservation Pollution
Content Type Text
Resource Type Article
Subject Health, Toxicology and Mutagenesis Pollution Medicine Toxicology
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