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Content Provider | World Health Organization (WHO)-Global Index Medicus |
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Author | Peng, Na Wang, Yanfeng Ye, Qifa Liang, Lei An, Yuxing Li, Qiwei Chang, Chunyu |
Description | Country affiliation: China Author Affiliation: Peng N ( Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Wuhan 430071, China); Wang Y ( Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Wuhan 430071, China.); Ye Q ( Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Wuhan 430071, China. Electronic address: yqf_china@163.com.); Liang L ( Guangzhou Sugarcane Industry Research Institute, Guangzhou 510316, China.); An Y ( Guangzhou Sugarcane Industry Research Institute, Guangzhou 510316, China.); Li Q ( Guangzhou Sugarcane Industry Research Institute, Guangzhou 510316, China.); Chang C ( Guangzhou Sugarcane Industry Research Institute, Guangzhou 510316, China) |
Abstract | Current superabsorbent hydrogels commercially applied in the disposable diapers have disadvantages such as weak mechanical strength, poor biocompatibility, and lack of antimicrobial activity, which may induce skin allergy of body. To overcome these hassles, we have developed novel cellulose based hydrogels via simple chemical cross-linking of quaternized cellulose (QC) and native cellulose in NaOH/urea aqueous solution. The prepared hydrogel showed superabsorbent property, high mechanical strength, good biocompatibility, and excellent antimicrobial efficacy against Saccharomyces cerevisiae. The presence of QC in the hydrogel networks not only improved their swelling ratio via electrostatic repulsion of quaternary ammonium groups, but also endowed their antimicrobial activity by attraction of sections of anionic microbial membrane into internal pores of poly cationic hydrogel leading to the disruption of microbial membrane. Moreover, the swelling properties, mechanical strength, and antibacterial activity of hydrogels strongly depended on the contents of quaternary ammonium groups in hydrogel networks. The obtained data encouraged the use of these hydrogels for hygienic application such as disposable diapers. |
File Format | HTM / HTML |
ISSN | 01448617 |
Journal | Carbohydrate Polymers |
Volume Number | 137 |
e-ISSN | 18791344 |
Language | English |
Publisher | Elsevier |
Publisher Date | 2016-02-10 |
Publisher Place | Great Britain (UK) |
Access Restriction | Subscribed |
Subject Keyword | Discipline Biochemistry__semicolon__materials Discipline Science Anti-infective Agents Chemistry Biocompatible Materials Cellulose Hydrogels Pharmacology Saccharomyces Cerevisiae Drug Effects Journal Article Research Support, Non-u.s. Gov't |
Content Type | Text |
Resource Type | Article |
Subject Domain (in MeSH) | Eukaryota Macromolecular Substances Complex Mixtures Biomedical and Dental Materials Chemical Actions and Uses |
Subject | Polymers and Plastics Materials Chemistry Organic Chemistry |
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