NDLI: Use of a central positron emitting reference source to improve the timing alignment of a singles list-mode small animal PET scanner

Content Provider	IEEE Xplore Digital Library
Author	McElroy, D.P. Thompson, C.J. Spanoudaki, V. Ziegler, S.I.
Copyright Year	2005
Description	Author affiliation: Nuklearmedizinische Klinik, Technische Univ. Munchen, Munich, Germany (McElroy, D.P.)
Abstract	To minimize the system-wide timing resolution of a PET scanner, and hence the applied coincidence window, a delay must be added to the signals from each crystal to compensate for inherent time differences between detectors. Without an absolute time reference, this must be been done iteratively. We propose using a new timing probe, consisting of a Ge-68 source imbedded in a plastic scintillator coupled to a fast PMT, to time-calibrate the MADPET-II small animal PET scanner. The probe provides a precise trigger signal with each positron decay and emission of 511 keV photons and, when placed in the center of the scanner, allows all crystals to be aligned to a common reference. MADPET-II is based on the one-to-one coupling of LSO crystals to APD detectors, each of which is read out by a dedicated electronic channel. Time stamps for each singles event are stored in list-mode format, allowing time offsets to be assigned directly to each detector. Signals from the probe were fed into an Ortec 934 CFD, and the trigger signals were digitised using the MADPET-II data acquisition system. Histograms generated by the time difference between the detection of 511 keV photons in the detectors and the corresponding positron decay in the probe give the time offsets for each crystal. After applying the offsets to the singles data, the system-wide timing resolution of the 256 channel MADPET-II prototype improved from 16.5 ns FWHM to 10.2 ns FWHM (450 keV threshold, F-18 flood source).
Starting Page	4
Ending Page	1623
File Size	191388
Page Count	1620
File Format	PDF
ISBN	0780392213
ISSN	10957863
DOI	10.1109/NSSMIC.2005.1596629
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-10-23
Publisher Place	Puerto Rico
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Timing Animals Positron emission tomography Photonic crystals Detectors Probes Signal resolution Added delay Delay effects Plastics
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Mr. Siddhartha Mukherjee siddhartha@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	ndl-support@iitkgp.ac.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Libarray of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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