NDLI: Sparse Bayesian multi-task learning for predicting cognitive outcomes from neuroimaging measures in Alzheimer's disease

Content Provider	IEEE Xplore Digital Library
Author	Jing Wan Zhilin Zhang Jingwen Yan Taiyong Li Rao, B.D. Shiaofen Fang Sungeun Kim Risacher, S.L. Saykin, A.J. Li Shen
Copyright Year	2012
Description	Author affiliation: Indiana University (Jing Wan; Jingwen Yan; Taiyong Li; Sungeun Kim; Risacher, S.L.; Saykin, A.J.; Li Shen) \|\| Purdue University (Shiaofen Fang) \|\| University of California, San Diego (Zhilin Zhang; Rao, B.D.)
Abstract	Alzheimer's disease (AD) is the most common form of dementia that causes progressive impairment of memory and other cognitive functions. Multivariate regression models have been studied in AD for revealing relationships between neuroimaging measures and cognitive scores to understand how structural changes in brain can influence cognitive status. Existing regression methods, however, do not explicitly model dependence relation among multiple scores derived from a single cognitive test. It has been found that such dependence can deteriorate the performance of these methods. To overcome this limitation, we propose an efficient sparse Bayesian multi-task learning algorithm, which adaptively learns and exploits the dependence to achieve improved prediction performance. The proposed algorithm is applied to a real world neuroimaging study in AD to predict cognitive performance using MRI scans. The effectiveness of the proposed algorithm is demonstrated by its superior prediction performance over multiple state-of-the-art competing methods and accurate identification of compact sets of cognition-relevant imaging biomarkers that are consistent with prior knowledge.
Starting Page	940
Ending Page	947
File Size	368357
Page Count	8
File Format	PDF
ISBN	9781467312264
ISSN	10636919
e-ISBN	9781467312288
e-ISBN	9781467312271
DOI	10.1109/CVPR.2012.6247769
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-06-16
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Correlation Algorithm design and analysis Neuroimaging Prediction algorithms Kernel Bayesian methods Magnetic resonance imaging
Content Type	Text
Resource Type	Article
Subject	Computer Vision and Pattern Recognition Software

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Mr. Siddhartha Mukherjee siddhartha@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	ndl-support@iitkgp.ac.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Libarray of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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