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Author Kachhara, R. ♦ Nair, S. ♦ Sandhyamani, S. ♦ Bhattacharya, R. N.
Source Sree Chitra Tirunal Institute for Medical Sciences & Technology
Content type Text
Publisher Neurologia Medico-chirurgica
File Format PDF
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health ♦ Diseases
Subject Domain (in MeSH) Musculoskeletal System ♦ Anatomy ♦ Neoplasms ♦ Skin and Connective Tissue Diseases ♦ Pathological Conditions, Signs and Symptoms ♦ Diseases
Subject Keyword Pathology
Abstract A 38-year-old male presented with an extremely rare primary osteogenic sarcoma, unassociated with Paget's disease or late effects of radiation, involving the sella and sphenoid sinus region. Complete excision of the tumor was achieved through an extended frontobasal approach. Postoperatively, six cycles of combination chemotherapy (adriamycin, ifosphamide, and cisplatin) followed by a total of 55 Gy local radiotherapy in 33 fractions was given. Primary osteogenic sarcoma should be considered in the differential diagnosis of the central skull base tumors. Osteogenic sarcoma, in general, has a bad prognosis, and should be managed aggressively with multimodality treatment including gross total surgical resection, combination chemotherapy, and radiotherapy.
Education Level UG and PG
Learning Resource Type Article
Educational Framework Medical Council of India (MCI)
Volume Number 39
Issue Number 7
Page Count 5
Starting Page 534
Ending Page 538