|Author||Jayabalan, M. ♦ Shalumon, K. T. ♦ Mitha, M. K. ♦ Ganesan, K. ♦ Epple, M.|
|Source||Sree Chitra Tirunal Institute for Medical Sciences & Technology|
|Publisher||Biomedical Materials (bristol, England)|
|Subject Domain (in DDC)||Technology ♦ Medicine & health|
|Subject Domain (in MeSH)||Biomedical and Dental Materials ♦ Chemicals and Drugs|
|Abstract||The effect of radiation processing and filler morphology on the biodegradation and biomechanical stability of a poly(propylene fumarate)/hydroxyapatite composite was investigated. Radiation processing influenced both cross-linking and biodegradation of the composites. Irradiation with a dose of 3 Mrad resulted in enhanced cross-linking, mechanical properties and a higher storage modulus which are favourable for dimensional stability of the implant. The particle morphology of the added hydroxyapatite in the highly cross-linked state significantly influenced the biomechanical and interfacial stability of the composites. Reorganization of agglomerated hydroxyapatite occurred in the cross-linked polymeric matrix under dynamic mechanical loading under simulated physiological conditions. Such a reorganization may increase the damping characteristics of the composite.|
|Education Level||UG and PG|
|Learning Resource Type||Article|
|Educational Framework||Medical Council of India (MCI)|
|Journal||Biomedical materials (Bristol, England)|
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