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Author Hassan, Haseeb ♦ Jukkarwala, Anis ♦ Iyer, Rajesh
Source Sree Chitra Tirunal Institute for Medical Sciences & Technology
Content type Text
Publisher Epilepsy Research
File Format PDF
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health ♦ Diseases
Subject Domain (in MeSH) Nervous System Diseases ♦ Diseases
Subject Keyword Neurology
Abstract The fixation-off sensitivity (FOS), an epileptic phenomenon induced by elimination of central vision and fixation, is rarely seen in symptomatic occipital lobe epilepsy. The cerebral mechanisms and the structural correlate underlying FOS remain unclear. We describe a 19-year-old male with persistent left sided FOS following perinatal insult. MRI revealed asymmetric changes with more gliosis and ulegyria over the left posterior occipital cortex corresponding to the topographic representation of the macula. We suggest that the extensive denervation of the area representing macula along with the presence of hyperexitable ulegyric cortex is responsible for the phenomenon of FOS. (C) 2011 Elsevier B.V. All rights reserved.
Education Level UG and PG
Learning Resource Type Article
Educational Framework Medical Council of India (MCI)
Volume Number 94
Issue Number 40910
Page Count 5
Starting Page 121
Ending Page 125