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Author Mohanty, M. ♦ Baby, S. ♦ Menon, K. V.
Source Sree Chitra Tirunal Institute for Medical Sciences & Technology
Content type Text
Publisher Journal of Biomaterials Applications
File Format PDF
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health ♦ Surgery & related medical specialties
Subject Domain (in MeSH) Equipment and Supplies ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment
Subject Keyword Medical Devices
Abstract Long-term tissue response to a metal device is described here. The components of a spinal fixation device were removed 6 years after implantation, following the need for revision surgery after a fall. Scanning electron microscopy (SEM) revealed changes in surface topography of the metal. Examination of the adjacent tissue showed a chronic inflammatory response with occasional metal debris. Immunohistochemistry identified the predominant macrophages and abundant neovascularization. The presence of macrophages in tissues adjacent to the implants, in an otherwise asymptomatic person, is noteworthy.
Education Level UG and PG
Learning Resource Type Article
Educational Framework Medical Council of India (MCI)
Volume Number 18
Issue Number 2
Page Count 13
Starting Page 109
Ending Page 121