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Author Sandhyamani, S.
Source Sree Chitra Tirunal Institute for Medical Sciences & Technology
Content type Text
Publisher Veterinary and Human Toxicology
File Format PDF
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health ♦ Pharmacology and therapeutics
Subject Domain (in MeSH) Cardiovascular Diseases ♦ Diseases ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment
Subject Keyword Experimental Medicine
Abstract Bonnet Monkeys (Macaca radiata) were maintained for up to 5 mo on protein-deficient diets that contained tapioca starch (cassava starch) as the source of carbohydrate. The animals developed mucopolysaccharidosis of blood vessels and cardiomyopathic changes in the heart. These changes were similar to the mucoid vasculopathy and cardiomyopathy seen in Kerala where tapioca is consumed as a staple diet by a large proportion of the people. The lesions were enhanced by longer duration of feeling the diet and in protein-deficient animals given additional amounts of tapioca starch. This indicates that protein-carbohydrate malnutrition does play a role in the induction of such cardiovascular disorders.
Education Level UG and PG
Learning Resource Type Article
Educational Framework Medical Council of India (MCI)
Journal Veterinary and Human Toxicology
Volume Number 33
Issue Number 5
Page Count 2
Starting Page 429
Ending Page 430