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Author Komath, Manoj ♦ Varma, H. K.
Source Sree Chitra Tirunal Institute for Medical Sciences & Technology
Content type Text
Publisher Indian Journal of Dental Research : Official Publication of Indian Society For Dental Research
File Format PDF
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Domain (in MeSH) Biomedical and Dental Materials ♦ Chemicals and Drugs
Subject Keyword Biomaterials
Abstract Calcium phosphate cements (CPC) are self setting and biocompatible bone substitute materials with potential applications in dentistry. However, its clinical use has been challenged by poor rheological properties. A novel formulation of CPC has been developed, which gives a fully injectable and cohesive paste. This work investigates the suitability of the new "fully injectable calcium phosphate cement" (FI-CPC) for dental applications. The cementing properties, material characteristics, and the rheological properties were tested using a battery of material characteristics methods. The biocompatibility was also evaluated as per ISO 7405. The setting time (20 min) and compressive strength (>11 Mpa) of FI-CPC satisfy the clinical requirements. It underwent setting without any exothermic reaction, keeping good dimensional stability. The cement paste could be extruded through a 18-gauge needle, easily and fully. It showed excellent cohesion when immersed in water. FI-CPC was seen to set into a micro-porous mass of hydroxyapatite, the mineral part of human dentin. It showed good attachment to dentin walls, when filled in tooth perforations. FI-CPC was found non-toxic, non-allergic, non-pyrogenic, and soft-tissue compatible. The study shows that FI-CPC provides a self setting bio-compatible paste with excellent rheological properties for surgical applications. The set cement provides good and stable sealing. The osteoconductive property is an added advantage. FI-CPC proves to be an ideal material for endodontic sealing/filling and periodontic repair.
Education Level UG and PG
Learning Resource Type Article
Educational Framework Medical Council of India (MCI)
Journal Indian journal of dental research : official publication of Indian Society for Dental Research
Volume Number 15
Issue Number 3
Page Count 7
Starting Page 89
Ending Page 95