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Author Thulaseedharan, J. V. ♦ Malila, N. ♦ Hakama, M. ♦ Esmy, P. O. ♦ Cheriyan, M. ♦ Swaminathan, R. ♦ Muwonge, R. ♦ Sankaranarayanan, Rengaswami
Source Sree Chitra Tirunal Institute for Medical Sciences & Technology
Content type Text
Publisher Asian Pacific Journal of Cancer Prevention : Apjcp
File Format PDF
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health ♦ Diseases
Subject Domain (in MeSH) Neoplasms ♦ Female Urogenital Diseases and Pregnancy Complications ♦ Diseases
Subject Keyword Oncology
Abstract Background: India shows some of the highest rates of cervical cancer worldwide, and more than 70% of the population is living in rural villages. Prospective cohort studies to determine the risk factors for cervical cancer are very rare from low and medium resource countries. The aim of this study was to quantify the effect of risk factors related to cervical cancer in a rural setting in South India. Material and methods: Sociodemographic and reproductive potential risk factors for cervical cancer were studied using the data from a cohort of 30,958 women who constituted the unscreened control group in a randomised screening trial in Dindigul district, Tamilnadu, India. The analysis was accomplished with the Cox proportional hazard regression model. Results: Women of increasing age (HR=2.4; 95% CI: 1.6, 3.8 in 50-59 vs 30-39), having many pregnancies (HR=7.1; 1.0, 52 in 4+ vs 0) and no education (HR=0.6; 0.2, 0.7 in high vs none) were found to be at significantly increased risk of cervical cancer. Conclusion: This cohort study gives very strong evidence to say that education is the fundamental factor among the sociodemographic and reproductive determinants of cervical cancer in low resource settings. Public awareness through education and improvements in living standards can play an important role in reducing the high incidence of cervical cancer in India. These findings further stress the importance of formulating public health policies aimed at increasing awareness and implementation of cervical cancer screening programmes.
Education Level UG and PG
Learning Resource Type Article
Educational Framework Medical Council of India (MCI)
Journal Asian Pacific journal of cancer prevention : APJCP
Volume Number 13
Issue Number 6
Page Count 2,987
Starting Page 5
Ending Page 2991