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Author Imaizumi, Katsumi ♦ Cho, Shuji ♦ Sugano, Michihiro ♦ Wada, Masafuto
Source J-STAGE
Content type Text
Publisher Japan Society for Bioscience, Biotechnology, and Agrochemistry
Language English
Abstract The uptake by liver slices of radioactive acetate, palmitate, stearate, linoleate and glycerol into glycerolipids was compared in fed and fasted (overnight, 16 hr) rats. The incorporation of $1-^{14}C-acetate$ into long-chain fatty acids and glycerolipids was depressed by fasting. There was a considerable decrease in the incorporation of $1-^{14}C-palmitate$ into triglyceride (TG) and that of $1-^{14}C-stearate$ into phosphatidylcholine (PC) in fasted liver slices. No such differences were observed with $1-^{14}C-linoleate.$ The incorporation of $1-^{14}C-glycerol$ into TG was slightly decreased, whereas that into PC and phosphatidylethanolamine (PE) was increased by fasting. These observations, together with those with the incorporation of the precursors into molecular species of TG, PC and PE, suggested that the changes in the fatty acid composition of glycerolipids by fasting may be governed by the changes in the availability of acyl moieties as well as in the relative balance of the pathways participating to formation of TG and phospholipids.
ISSN 00021369
Learning Resource Type Article
Publisher Date 1972-01-01
e-ISSN 18811280
Journal Agricultural and Biological Chemistry(bbb1961)
Volume Number 36
Issue Number 10
Page Count 7
Starting Page 1783
Ending Page 1789


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