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Author Neittaanmäki-Perttu, Noora ♦ Grönroos, Mari ♦ Karppinen, Toni ♦ Snellman, Erna ♦ Rissanen, Pekka
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Society for the Publication of Acta Dermato-Venereologica
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Technology ♦ Medicine & health ♦ Diseases
Subject Keyword Discipline Sexually Transmitted Diseases ♦ Discipline Dermatology
Abstract Daylight-mediated photodynamic therapy (DL-PDT) is considered as effective as conventional PDT using artificial light (light-emitting diode (LED)-PDT) for treatment of actinic keratoses (AK). This randomized prospective non-sponsored study assessed the cost-effectiveness of DL-PDT compared with LED-PDT. Seventy patients with 210 AKs were randomized to DL-PDT or LED-PDT groups. Effectiveness was assessed at 6 months. The costs included societal costs and private costs, including the time patients spent in treatment. Results are presented as incremental cost-effectiveness ratio (ICER). The total costs per patient were significantly lower for DL-PDT ( 132) compared with LED-PDT ( 170), giving a cost saving of 38 (p = 0.022). The estimated probabilities for patients' complete response were 0.429 for DL-PDT and 0.686 for LED-PDT; a difference in probability of being healed of 0.257. ICER showed a monetary gain of 147 per unit of effectiveness lost. DL-PDT is less costly and less effective than LED-PDT. In terms of cost-effectiveness analysis, DL-PDT provides lower value for money compared with LED-PDT.
Description Country affiliation: Finland
Author Affiliation: Neittaanmäki-Perttu N ( Department of Dermatology and Allergology, Helsinki University and Helsinki University Hospital, FIN-00029 Helsinki, Finland. noora.neittaanmaki@fimnet.fi.)
ISSN 00015555
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2016-02-01
Publisher Place Sweden
e-ISSN 16512057
Journal Acta Dermato Venereologica
Volume Number 96
Issue Number 2


Source: WHO-Global Index Medicus