|Author||Mackay, N. R.|
|Source||United States Department of Energy Office of Scientific and Technical Information|
|Subject Keyword||BIOLOGY AND MEDICINE ♦ BETA DECAY ♦ BLADDER ♦ CALCIUM BROMIDES ♦ CANCER ♦ GAMMA RADIATION ♦ MAN ♦ MATHEMATICS ♦ MEASURED VALUES ♦ MEDICINE ♦ RADIATION DOSES ♦ RADIATION INJURIES ♦ RADIOISOTOPES ♦ RADIOTHERAPY ♦ RECOVERY ♦ SOLUTIONS ♦ SURVIVAL TIME ♦ TISSUES|
|Abstract||The techniques used at the Royal Marsden Hospital for the intracavitary irradiation of the bladder with radioactive fluids are reviewed. A modification of one of these techniques introduced in an attempt to lower the incidence of irradiation-produced damage is described. A solution of calcium bromide-82 contained in a latex rubber balloon is used to treat the bladder mucosa continuously for 96 hours, a surface gamma dose of 4,200 rads and beta dose of 1,000 rads being delivered. The dose-rates are at least ten times less than those used in previous techniques. The results from this treatment for a series of 20 patients are compared with those from earlier techniques. No high dose effects were observed and complete disappearance of all tumors occurred after three months in nine cases. Survival times for the different treatment techniques are tabulated. The method of calculating the radiation dose to the bladder mucosa is outlined. (auth)|
|Learning Resource Type||Article|
|Journal||Brit. J. Radiol.|
|Organization||Royal Cancer Hospital, London ♦ and Royal Marsden Hospital, London|
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