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Author Kumar, Arunachalam
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Wolters Kluwer Medknow Publications
File Format HTM / HTML
Date Created 2017-11-07
Copyright Year ©1984
Language English
Subject Domain (in LCC) RL1-803
Subject Keyword Medicine ♦ Dermatology
Abstract Two hundred and forty nine eggs of the white leghorn were injected on day 3,4 and 5 their incubation, with 0.03 mgtkg egg weight, of vincristine sulphate. Most embryos were removed 24, 48 and 72 hours after administration and examined histologically. A few eggs were opened on day 18 of incubation. The results of this study indicate that the drug is embryo-lethal in a majority of chicks and those that survive the toxic effects of vincristine show pronounced neuro/ectodermal dysplasias. Malformations of the neural tube and neural crest with depigmentation of the feathers and their loose anchoring were observed. The possible mechanism of these dysplasias is discussed.
ISSN 03786323
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 1984-01-01
e-ISSN 03786323
Journal Indian Journal of Dermatology, Venereology and Leprology
Volume Number 50
Issue Number 4
Page Count 1
Starting Page 142
Ending Page 143


Source: Directory of Open Access Journals (DOAJ)