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Author Agrawal, Mukesh ♦ Madabhushi, Sujani C. ♦ Doppalapudi, Kiran Kumar ♦ Nugoori, Uma Swarup
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Wolters Kluwer Medknow Publications
File Format HTM / HTML
Date Created 2018-06-06
Copyright Year ©2015
Language English
Subject Domain (in LCC) R
Subject Keyword Hemoglobin Q India ♦ Double heterozygous ♦ Medicine ♦ Hemoglobin D Punjab ♦ High-performance liquid chromatography (HPLC)
Abstract Hemoglobinopathies constitute the most common genetic diseases in the world. In India, both beta-thalassemia and structural hemoglobin variants, such as hemoglobin S (HbS), hemoglobin D (HbD), and hemoglobin E (HbE), are common and pose significant health problem, these variants show heterozygous state along with beta-thalassemia. Compound heterozygosity among hemoglobin variants is very rare. Cation-exchange high-performance liquid chromatography (CE HPLC) provides accurate and reliable diagnosis of various hemoglobin variants. Here, we report an index case of double heterozygous hemoglobinopathy, hemoglobin Q (HbQ) India/HbD Punjab (ααQ India-ββD Punjab) using CE HPLC. This is the fifth report of double heterozygosity for HbQ India/HbD Punjab globally and fourth case report from India to the best of our knowledge.
ISSN 22781889
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Report
Publisher Date 2015-01-01
e-ISSN 22781889
Journal Journal of Dr. NTR University of Health Sciences
Volume Number 4
Issue Number 4
Page Count 3
Starting Page 266
Ending Page 268

Source: Directory of Open Access Journals (DOAJ)