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Author Surrey, Eric S. ♦ Schoolcraft, William B.
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Springer
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Human anatomy, cytology, histology ♦ Human physiology ♦ Pharmacology and therapeutics ♦ Diseases ♦ Gynecology, obstetrics, pediatrics & geriatrics ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Urogenital System ♦ Anatomy ♦ Eukaryota ♦ Organisms ♦ Female Urogenital Diseases and Pregnancy Complications ♦ Diseases ♦ Diagnosis ♦ Therapeutics ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Physical Phenomena ♦ Reproductive and Urinary Physiological Phenomena ♦ Biological Sciences
Subject Keyword Discipline Reproductive Medicine ♦ Discipline Genectics ♦ Embryo Transfer ♦ Endometriosis ♦ Surgery ♦ Fertilization In Vitro ♦ Pregnancy Outcome ♦ Female ♦ Humans ♦ Oocytes ♦ Physiology ♦ Pregnancy ♦ Pregnancy Rate ♦ Retrospective Studies ♦ Time Factors ♦ Journal Article ♦ Review
Abstract PURPOSE: To assess the effect on cycle outcome of surgery for endometriosis performed in the 6 months prior to in vitro fertilization-embryo transfer (IVF-ET). METHODS: Retrospective analysis of all patients with a primary diagnosis of endometriosis undergoing IVF-ET during 12 consecutive months. The setting included tertiary care assisted reproductive technology program. Ninety-five consecutive cycles in candidates for autologous IVF-ET who had undergone surgical resection of endometriosis within 60 months of oocyte retrieval were evaluated. Five patients with persistent or recurrent endometriomas > 3 cm at the time of IVF-ET were excluded. Patients were divided into two groups based on the interval between the most recent surgical intervention and oocyte aspiration-Group I: < or = 6 months' interval (19 cycles); Group II: > 6 months' interval (76 cycles). RESULTS: Mean intervals between surgery and oocyte aspiration were significantly different between the groups (Gr I: 3.7 +/- 0.3 months; Gr II: 21.8 +/- 1.6 months; p < 0.001). There were no significant differences between groups with regards to age, extent of endometriosis, or results of ovarian stimulation and oocyte aspiration. Ongoing pregnancy rates (Gr I: 63.2%; Gr. II: 60.5%) were similar. Regression analyses revealed no correlation between implantation rates and either endometriosis score (r = -0.09) or surgery-oocyte aspiration interval (r = -0.13). CONCLUSIONS: The interval between surgical management of endometriosis and oocyte aspiration did not have an impact on IVF-ET cycle outcome in the absence of significant persistent or recurrent ovarian disease. Any effect of surgery on enhancing spontaneous conception may be overcome by the inherently greater impact of IVF-ET on implantation and pregnancy.
Description Country affiliation: United States
Author Affiliation: Surrey ES ( Colorado Center for Reproductive Medicine, Englewood, Colorado, USA.
ISSN 10580468
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2003-09-01
Publisher Place Netherlands
e-ISSN 15737330
Journal Journal of Assisted Reproduction and Genetics
Volume Number 20
Issue Number 9

Source: WHO-Global Index Medicus