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Author Duvan, Candan Iltemir ♦ Ozmen, Batuhan ♦ Satiroglu, Hakan ♦ Atabekoglu, Cem Somer ♦ Berker, Bulent
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Springer
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Human physiology ♦ Pharmacology and therapeutics ♦ Diseases ♦ Gynecology, obstetrics, pediatrics & geriatrics ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Eukaryota ♦ Organisms ♦ Organic Chemicals ♦ Polycyclic Compounds ♦ Chemical Actions and Uses ♦ Chemicals and Drugs ♦ Therapeutics ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Physiological Phenomena ♦ Reproductive and Urinary Physiological Phenomena ♦ Biological Sciences ♦ Persons ♦ Persons
Subject Keyword Discipline Reproductive Medicine ♦ Discipline Genectics ♦ Anti-inflammatory Agents, Non-steroidal ♦ Administration & Dosage ♦ Anti-inflammatory Agents ♦ Aspirin ♦ Embryo Implantation ♦ Drug Effects ♦ Prednisolone ♦ Pregnancy Rate ♦ Sperm Injections, Intracytoplasmic ♦ Adult ♦ Dose-response Relationship, Drug ♦ Female ♦ Humans ♦ Pregnancy ♦ Prospective Studies ♦ Journal Article ♦ Randomized Controlled Trial
Abstract PURPOSE: To investigate the effects of short-term low-dose aspirin and/or steroid use on implantation and pregnancy rates in nonselected intracytoplasmic sperm injection (ICSI) cycles. METHODS: Two-hundred patients undergoing ICSI for their first cycle were enrolled in this study. Participants were then randomized into four groups on the embryo transfer day. Aspirin (100 mg/day) in group A, prednisolone (10 mg/day) in group B, aspirin along with prednisolone in group C were given while placebo was administrated to group D. RESULT: There were no statistically significant differences recorded in the demographic, ovulation induction cycle characteristics between groups. Mean transferred embryo number and mean top quality embryo number were similar among study groups. There were no statistical differences in implantation and pregnancy rates between study groups. CONCLUSION: Administration of low-dose aspirin and prednisolone alone or concomitant as a standard treatment have no positive effects on implantation and/or pregnancy rates.
Description Country affiliation: Turkey
Author Affiliation: Duvan CI ( Faculty of Medicine, Department of Obstetrics and Gynecology, Faith University, Ankara, Turkey.
ISSN 10580468
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2006-01-01
Publisher Place Netherlands
e-ISSN 15737330
Journal Journal of Assisted Reproduction and Genetics
Volume Number 23
Issue Number 1

Source: WHO-Global Index Medicus