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Author Sousa lages, Adriana De ♦ Francisco portela ♦ Isabel paiva ♦ Carrilho, Francisco ♦ Patrícia oliveira
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Bioscientifica
File Format HTM / HTML
Date Created 2017-04-11
Copyright Year ©2017
Language English
Subject Domain (in LCC) RC648-665
Subject Keyword Clinical endocrinology ♦ Diseases of the endocrine glands ♦ Internal medicine ♦ Medicine ♦ Specialties of internal medicine
Abstract Insulinomas are the most frequent cause of hyperinsulinaemic hypoglycaemia. Although surgical enucleation is the standard treatment, a few other options are available to high-risk patients who are elderly or present with co-morbidities. We present a case report of an 89-year-old female patient who was admitted to the emergency department due to recurrent hypoglycaemia, especially during fasting. Laboratory work-up raised the suspicion of hyperinsulinaemic hypoglycaemia, and abdominal CT scan revealed a 12 mm nodular hypervascular lesion of the pancreatic body suggestive of neuroendocrine tumour. The patient was not considered a suitable candidate for surgery, and medical therapy with diazoxide was poorly tolerated. Endoscopic ultrasound-guided ethanol ablation therapy was performed and a total of 0.6 mL of 95% ethanol was injected into the lesion by a transgastric approach; no complications were reported after the procedure. At 5 months of follow-up, no episodes of hypoglycaemia were reported, no diazoxide therapy was necessary, and revaluation abdominal CT scan revealed a pancreatic nodular lesion with a size involution of about half of its original volume. The patient is regularly followed-up at the endocrinology clinic and shows a significant improvement in her wellbeing and quality of life.
ISSN 20520573
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2017-04-01
e-ISSN 20520573
Journal Endocrinology, Diabetes & Metabolism Case Reports
Volume Number 1
Issue Number 1
Page Count 5
Starting Page 1
Ending Page 5


Source: Directory of Open Access Journals (DOAJ)