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Author Péton, Vincent ♦ Nordengrün, Maria ♦ Darisipudi, Murthy N. ♦ Bröker, Barbara M.
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher MDPI AG
File Format PDF
Date Created 2018-08-16
Copyright Year ©2018
Language English
Subject Domain (in LCC) QH301-705.5
Subject Keyword Infection ♦ Dendritic cells ♦ Biology ♦ Innate immunity ♦ Immune evasion ♦ Science ♦ S. aureus ♦ Adaptive immunity
Abstract Staphylococcus aureus (S. aureus) is a dangerous pathogen as well as a frequent colonizer, threatening human health worldwide. Protection against S. aureus infection is challenging, as the bacteria have sophisticated strategies to escape the host immune response. To maintain equilibrium with S. aureus, both innate and adaptive immune effector mechanisms are required. Dendritic cells (DCs) are critical players at the interface between the two arms of the immune system, indispensable for inducing specific T cell responses. In this review, we highlight the importance of DCs in mounting innate as well as adaptive immune responses against S. aureus with emphasis on their role in S. aureus-induced respiratory diseases. We also review what is known about mechanisms that S. aureus has adopted to evade DCs or manipulate these cells to its advantage.
ISSN 20762607
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2018-08-01
e-ISSN 20762607
Journal Microorganisms
Volume Number 6
Issue Number 3
Starting Page 87

Source: Directory of Open Access Journals (DOAJ)