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Author Hai-Ying Tang ♦ Hao Wu ♦ Jing-Wei Mao ♦ Lei Zhu ♦ Na Li ♦ Ying-De Wang
Source IEEE Xplore Digital Library
Content type Text
Publisher Institute of Electrical and Electronics Engineers, Inc. (IEEE)
File Format PDF
Copyright Year ©2014
Language English
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science ♦ Technology ♦ Engineering & allied operations
Subject Keyword Conferences ♦ Automation
Abstract Aim: To investigate the clinical therapeutic efficacy of saccharomyces boulardii(Sb) in combination with mesalazine in patients with mild to moderate ulcerative colitis (UC). Methods: Sixty patients aged 18 to 75 years with mild to moderate UC were divided into two groups, the combination group and the mesalazine group. Clinical remission rate (CRR) was calculated with the formula: CRR= number of complete remission cases + number of effective cases)/all cases. The clinical symptom score (CSS), endoscopic score (ES) and histopathological score (HS) were recorded before and after treatment. Result: After two week's treatment, the CSS in the combination group was significantly decreased (P<;0.05), but in the mesalazine group it showed no significant changes (P>0.05). After four week's treatment, the CSS in both combination group and mesalazine group was significantly decreased(P<;0.05). After 8 week's treatment, the CSS, ES and HS in the combination group were significantly lower than those in the mesalazine group(P<;0.05). CRR in the combination group (46.7%) was significantly higher than that in the mesalazine group (20.0%) after 8 weeks' treatment (P<;0.05). Conclusion: Saccharomyces boulardii in combination with mesalazine is faster and more effective in improving clinical symptoms, endoscopic and histopathological changes in patients with mild to moderate UC than using mesalazine alone.
Description Author affiliation: Dept. of Gastroenterology, Dalian Med. Univ., Dalian, China (Hai-Ying Tang; Hao Wu; Jing-Wei Mao; Lei Zhu; Na Li; Ying-De Wang)
ISBN 9781479928378
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research ♦ Reading
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2014-06-18
Publisher Place Taiwan
Rights Holder Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Size (in Bytes) 211.19 kB
Page Count 4
Starting Page 734
Ending Page 737


Source: IEEE Xplore Digital Library