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Author Jiegang Peng ♦ Zhaoying Zhou ♦ Qiang Xu ♦ Dongxu Zhang ♦ Junhua Zhu
Source IEEE Xplore Digital Library
Content type Text
Publisher Institute of Electrical and Electronics Engineers, Inc. (IEEE)
File Format PDF
Copyright Year ©2007
Language English
Subject Domain (in DDC) Natural sciences & mathematics ♦ Life sciences; biology ♦ Biochemistry ♦ Technology ♦ Medicine & health
Subject Keyword Temperature sensors ♦ Heart rate ♦ Animal structures ♦ Automatic control ♦ Oncology ♦ Control systems ♦ Blood pressure ♦ Temperature control ♦ Hyperthermia ♦ Biomedical monitoring
Abstract Objectives. To evaluate the safety property of a novel whole-body perfusion system for hyperthermia in oncology, the organ temperature, blood pressure and heart rate response to extracorporeal circulation blood temperature were investigated in animal experimentation. Materials and Methods. The device is an apparatus and method for a perfusion hyperthermia treatment of a patient which obtains a body fluid having a particular temperature. The device can automatically monitors and controls a perfusion hyperthermia treatment. The device includes programmed computers, mechanical subsystems and sensor subsystems. Two dogs were used as experimental animals. Results. There is no over control of the temperature of blood and the control max error of the temperature of blood is 0.16degC using the whole-body perfusion system. As the temperature of blood increase, the temperatures of dog organ increase. When the temperature of blood maintain constant, the temperatures of dog organ would be drive to stabilization stage. As the temperature of blood changes, the blood pressure and heart rate of dog would not be clearly changed. Conclusions. Changes in the temperature of blood, as induced by the new computerized perfusion system developed by ourselves, may be secure for organ and heart function of animal. The control index properties of the system are fit for hyperthermia in oncology.
Description Author affiliation: Sch. of Autom., Univ. of Electron. Sci. & Technol. of China, Chengdu (Jiegang Peng)
ISBN 1424411203
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research ♦ Reading
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2007-07-06
Publisher Place China
Rights Holder Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Size (in Bytes) 601.68 kB
Page Count 4
Starting Page 1080
Ending Page 1083


Source: IEEE Xplore Digital Library