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Author Nor, M.M. ♦ Bais, B. ♦ Aziz, N.A. ♦ Rahim, R.A. ♦ Majlis, B.Y.
Source IEEE Xplore Digital Library
Content type Text
Publisher Institute of Electrical and Electronics Engineers, Inc. (IEEE)
File Format PDF
Copyright Year ©2012
Language English
Subject Domain (in DDC) Natural sciences & mathematics ♦ Physics ♦ Electricity & electronics ♦ Technology ♦ Engineering & allied operations ♦ Applied physics
Subject Keyword Sugar ♦ Force ♦ Biochemistry ♦ Biosensors ♦ Immune system ♦ Force measurement
Abstract Microcantilever-based glucose sensor is a state-of-art sensor that has been widely investigated for biosensing applications. This work focuses on the preliminary study of correlation of the glucose reaction and the induced force on the microcantilever sensor by measuring the induced mass changes due to the glucose reaction. The induced force is then used to test the fabricated microcantilever sensor for glucose detection. Gold-coated glass slides were used as the immobilization sites for glucose oxidase enzyme. The reaction of the glucose oxidase enzyme and ß-D glucose was observed by injecting 5 mM glucose solution on 0.3 mL immobilized enzyme on three samples. The resulted mass changes, ranging from 151.87 mg to 180. 14 mg for the three samples, indicate a good correlation between the enzyme-glucose reaction and the induced mass change. The induced forces of 0.28 μN to 0.29 μN, converted from the mass changes of the glucose-enzyme reaction, is in a range of interactive force values commonly found in biochemical detection applications.
Description Author affiliation: Institute of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan Malaysia (UKM), 43600 UKM Bangi, Selangor, Malaysia (Nor, M.M.; Bais, B.; Aziz, N.A.; Majlis, B.Y.) || Dept. of Electrical Electrical and Computer Engineering, Kulliyyah of Engineering, International Islamic University Malaysia (IIUM) (Rahim, R.A.)
ISBN 9781467323956
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research ♦ Reading
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2012-09-19
Publisher Place Malaysia
Rights Holder Institute of Electrical and Electronics Engineers, Inc. (IEEE)
e-ISBN 9781467323963
Size (in Bytes) 918.77 kB
Page Count 4
Starting Page 340
Ending Page 343


Source: IEEE Xplore Digital Library