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Author Mackillop, William J. ♦ Kong, Weidong ♦ Brundage, Michael ♦ Hanna, Timothy P. ♦ Zhang-Salomons, Jina ♦ McLaughlin, Pierre-Yves ♦ Tyldesley, Scott
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword RADIOLOGY AND NUCLEAR MEDICINE ♦ BENCHMARKS ♦ COMPARATIVE EVALUATIONS ♦ DIAGNOSIS ♦ LIFETIME ♦ MATHEMATICAL MODELS ♦ MONITORING ♦ NEOPLASMS ♦ ONTARIO ♦ PATIENTS ♦ PLANNING ♦ POPULATIONS ♦ RADIOTHERAPY
Abstract Purpose: Estimates of the appropriate rate of use of radiation therapy (RT) are required for planning and monitoring access to RT. Our objective was to compare estimates of the appropriate rate of use of RT derived from mathematical models, with the rate observed in a population of patients with optimal access to RT. Methods and Materials: The rate of use of RT within 1 year of diagnosis (RT{sub 1Y}) was measured in the 134,541 cases diagnosed in Ontario between November 2009 and October 2011. The lifetime rate of use of RT (RT{sub LIFETIME}) was estimated by the multicohort utilization table method. Poisson regression was used to evaluate potential barriers to access to RT and to identify a benchmark subpopulation with unimpeded access to RT. Rates of use of RT were measured in the benchmark subpopulation and compared with published evidence-based estimates of the appropriate rates. Results: The benchmark rate for RT{sub 1Y}, observed under conditions of optimal access, was 33.6% (95% confidence interval [CI], 33.0%-34.1%), and the benchmark for RT{sub LIFETIME} was 41.5% (95% CI, 41.2%-42.0%). Benchmarks for RT{sub LIFETIME} for 4 of 5 selected sites and for all cancers combined were significantly lower than the corresponding evidence-based estimates. Australian and Canadian evidence-based estimates of RT{sub LIFETIME} for 5 selected sites differed widely. RT{sub LIFETIME} in the overall population of Ontario was just 7.9% short of the benchmark but 20.9% short of the Australian evidence-based estimate of the appropriate rate. Conclusions: Evidence-based estimates of the appropriate lifetime rate of use of RT may overestimate the need for RT in Ontario.
ISSN 03603016
Educational Use Research
Learning Resource Type Article
Publisher Date 2015-04-01
Publisher Place United States
Journal International Journal of Radiation Oncology, Biology and Physics
Volume Number 91
Issue Number 5


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