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Author Alici, K.B.
Sponsorship IEEE Nanotechnology Council
Source IEEE Xplore Digital Library
Content type Text
Publisher Institute of Electrical and Electronics Engineers, Inc. (IEEE)
File Format PDF
Copyright Year ©2002
Language English
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science ♦ Natural sciences & mathematics ♦ Physics ♦ Electricity & electronics
Subject Keyword Metamaterials ♦ Proteins ♦ Substrates ♦ Plasmons ♦ Arrays ♦ Gold ♦ Spectroscopy ♦ thin films ♦ Avidin ♦ biosensor ♦ biotin ♦ collective excitation ♦ enhancement factor ♦ fano resonance ♦ metamaterial ♦ microscopy ♦ monolayer ♦ nanoantenna ♦ near-field effects ♦ self-assembly ♦ spectroscopy ♦ streptavidin ♦ surface-enhanced infrared absorption (SEIRA) ♦ surface plasmon ♦ temporal-coupled mode theory
Abstract We present spectral hybridization of organic and inorganic resonant materials and related bio-sensing mechanism. We utilized a bound protein (streptavidin) and a Fano-resonant metasurface to illustrate the concept. The technique allows us to investigate the vibrational modes of the streptavidin and how they couple to the underlying metasurface. This optical, label-free, nonperturbative technique is supported by a coupled mode-theory analysis that provides information on the structure and orientation of bound proteins. We can also simultaneously monitor the binding of analytes to the surface through monitoring the shift of the metasurface resonance. All of this data opens up interesting opportunities for applications in biosensing, molecular electronics and proteomics.
Description Author affiliation :: Univ. of Texas at Austin, Austin, TX, USA
ISSN 1536125X
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2014-01-01
Publisher Place U.S.A.
Rights Holder Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Volume Number 13
Issue Number 2
Size (in Bytes) 573.33 kB
Page Count 6
Starting Page 216
Ending Page 221


Source: IEEE Xplore Digital Library