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Author Zhao, Jizheng ♦ Tomasi, Dardo ♦ Wiers, Corinde E. ♦ Shokri-Kojori, Ehsan ♦ Demiral, Şükrü B. ♦ Zhang, Yi ♦ Volkow, Nora D. ♦ Wang, Gene-Jack
Editor Mangel, Stuart C.
Source Hindawi
Content type Text
Publisher Hindawi
File Format PDF
Copyright Year ©2017
Language English
Abstract Negative urgency (NU) and positive urgency (PU) are implicated in several high-risk behaviors, such as eating disorders, substance use disorders, and nonsuicidal self-injury behavior. The current study aimed to explore the possible link between trait of urgency and brain activity at rest. We assessed the amplitude of low-frequency fluctuations (ALFF) of the resting-state functional magnetic resonance imaging (fMRI) signal in 85 healthy volunteers. Trait urgency measures were related to ALFF in the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, ventral and dorsal medial frontal cortex, anterior cingulate, and posterior cingulate cortex/precuneus. In addition, trait urgency measures showed significant correlations with the functional connectivity of the posterior cingulate cortex/precuneus seed with the thalamus and midbrain region. These findings suggest an association between intrinsic brain activity and impulsive behaviors in healthy humans.
ISSN 20905904
Learning Resource Type Article
Publisher Date 2017-10-31
Rights License This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
e-ISSN 16875443
Journal Neural Plasticity
Volume Number 2017
Page Count 9


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