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Author Geertsen, Svend Sparre ♦ Kirk, Henrik ♦ Nielsen, Jens Bo ♦ {"id":"U87634851","contrib_type":"Guest Editor","orcid":"http://orcid.org/0000-0003-4497-3616","surname":"Fiori","given-names":"Simona"}
Source Hindawi
Content type Text
Publisher Hindawi
File Format PDF
Copyright Year ©2018
Language English
Abstract We recently showed that impaired gait function in adults with cerebral palsy (CP) is associated with reduced rate of force development in ankle dorsiflexors. Here, we explore potential mechanisms. We investigated the suppression of antagonist excitability, calculated as the amount of soleus H-reflex depression at the onset of ankle dorsiflexion compared to rest, in 24 adults with CP (34.3 years, range 18–57; GMFCS 1.95, range 1–3) and 15 healthy, age-matched controls. Furthermore, the central common drive to dorsiflexor motoneurons during a static contraction in the two groups was examined by coherence analyses. The H-reflex was significantly reduced by 37% at the onset of dorsiflexion compared to rest in healthy adults (P<0.001) but unchanged in adults with CP (P=0.91). Also, the adults with CP had significantly less coherence. These findings suggest that the ability to suppress antagonist motoneuronal excitability at movement onset is impaired and that the central common drive during static contractions is reduced in adults with CP.
ISSN 20905904
Learning Resource Type Article
Publisher Date 2018-10-09
Rights License This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
e-ISSN 16875443
Journal Neural Plasticity
Volume Number 2018
Page Count 11


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