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Author Garcin, Edwige B. ♦ Bornet, Olivier ♦ Elantak, Latifa ♦ Vita, Nicolas ♦ Pieulle, Laetitia ♦ Guerlesquin, Francoise ♦ Sebban-Kreuzer, Corinne
Source Hyper Articles en Ligne (HAL)
Content type Text
Publisher American Society for Biochemistry and Molecular Biology
File Format PDF
Language English
Subject Keyword sdv ♦ Life Sciences [q-bio] ♦ Life Sciences [q-bio]/Biochemistry, Molecular Biology ♦ Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Abstract Background: TDOR are ubiquitous and catalyze important cell redox reactions. Results: Dtrx presents atypical physicochemical properties and a positive surface around its active site, suggesting a specificity for it(s) substrate(s). Conclusion: Active site histidine plays an important role in the molecular mechanism of Dtrx catalysis. Significance: Structural and functional studies of such atypical systems will give new insights into the TDOR catalytic mechanism.
ISSN 00219258
Educational Use Research
Learning Resource Type Article
Publisher Date 2012-01-13
e-ISSN 1083351X
Journal Journal of Biological Chemistry
Volume Number 287
Issue Number 3
Page Count 10
Starting Page 1688
Ending Page 1697