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Author Natale, Kristen E. ♦ Royer, Michael C. ♦ Rush, Walter L. ♦ Lupton, George P.
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Wiley
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Human anatomy, cytology, histology ♦ Human physiology ♦ Diseases ♦ Surgery & related medical specialties ♦ Gynecology, obstetrics, pediatrics & geriatrics ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Body Regions ♦ Urogenital System ♦ Tissues ♦ Cells ♦ Integumentary System ♦ Anatomy ♦ Eukaryota ♦ Organisms ♦ Neoplasms ♦ Female Urogenital Diseases and Pregnancy Complications ♦ Skin and Connective Tissue Diseases ♦ Diseases ♦ Diagnosis ♦ Surgical Procedures, Operative ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Reproductive and Urinary Physiological Phenomena ♦ Biological Sciences ♦ Persons ♦ Persons
Subject Keyword Discipline Pathology ♦ Discipline Dermatology ♦ Decidua ♦ Pathology ♦ Endometriosis ♦ Diagnosis ♦ Skin Diseases ♦ Abdominal Wall ♦ Adult ♦ Biological Markers ♦ Metabolism ♦ Cesarean Section ♦ Cicatrix ♦ Diagnosis, Differential ♦ Epithelioid Cells ♦ Female ♦ Humans ♦ Perineum ♦ Postpartum Period ♦ Skin ♦ Skin Neoplasms ♦ Case Reports ♦ Journal Article
Abstract Cutaneous deciduosis represents a rare manifestation of cutaneous endometriosis in which typical endometrial glands and stroma are morphologically and physiologically transformed under hormonal influence. The transformed glands and stroma usually take on the microscopic appearance of uterine decidua but may mimic malignancy. We describe two cases of cutaneous deciduosis that presented in the post-partum period, but biopsies were not performed until a much later date. The first lesion arose on the perineum of a 31-year-old female after vaginal delivery, but a biopsy was not performed until 6 years after presentation. The second lesion grew in a cesarean section scar of a 26-year-old female with a history of ovarian adnexal endometriosis. Clinically described as a persistent post-operative hematoma, the lesion throbbed in synchrony with her menstrual cycles; a biopsy was also performed 6 years after presentation. Histopathologically, both specimens showed similar findings. Sections showed a multinodular proliferation of pale-staining epithelioid cells without significant nuclear atypia or conspicuous mitotic figures. Both showed focal glands that ranged from slit-like to slightly dilated and that contained a flattened epithelial lining without atypia. These unusual cases are presented to instruct about the pathologic findings of this entity in order to prevent the unnecessary diagnosis of malignancy.
Description Country affiliation: United States
Author Affiliation: Natale KE ( Department of Pathology, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA. Kristen.Natale@med.navy.mil)
ISSN 03036987
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Case study ♦ Article
Publisher Date 2012-08-01
Publisher Place United States
e-ISSN 16000560
Journal Journal of Cutaneous Pathology
Volume Number 39
Issue Number 8


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Source: WHO-Global Index Medicus