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Author Wu, I-Hui ♦ Yu, Hsi-Yu ♦ Liu, Chih-Ho ♦ Chen, Yih-Sharng ♦ Wang, Shoei-Shun ♦ Lin, Fang-Yue
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Wiley
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Philosophy & psychology ♦ Psychology ♦ Social sciences ♦ Economics ♦ Microeconomics & related topics ♦ Social problems & services; associations ♦ Social welfare problems & services ♦ Natural sciences & mathematics ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Human physiology ♦ Incidence & prevention of disease ♦ Diseases ♦ Surgery & related medical specialties ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Eukaryota ♦ Organisms ♦ Cardiovascular Diseases ♦ Pathological Conditions, Signs and Symptoms ♦ Diseases ♦ Diagnosis ♦ Surgical Procedures, Operative ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Psychological Phenomena and Processes ♦ Psychiatry and Psychology ♦ Physical Phenomena ♦ Biological Sciences ♦ Persons ♦ Persons ♦ Health Care Economics and Organizations ♦ Health Care Quality, Access, and Evaluation ♦ Health Care ♦ Geographic Locations ♦ Geographic Locations
Subject Keyword Discipline Cardiology ♦ Discipline Surgery ♦ Aneurysm, Dissecting ♦ Surgery ♦ Aortic Aneurysm, Thoracic ♦ Acute Disease ♦ Adult ♦ Age Factors ♦ Aged ♦ Aged, 80 And Over ♦ Drug Therapy ♦ Mortality ♦ Decision Making ♦ Female ♦ Geriatric Assessment ♦ Humans ♦ Insurance, Health ♦ Male ♦ Middle Aged ♦ Postoperative Period ♦ Registries ♦ Retrospective Studies ♦ Survival Analysis ♦ Taiwan ♦ Epidemiology ♦ Time Factors ♦ Treatment Outcome ♦ Journal Article
Abstract BACKGROUND: Acute aortic dissection is usually presented as a surgical emergent condition with high mortality rate. Whether any patient of an advanced age suffering from acute aortic type A dissection or complicated type B dissection should be referred for surgery still deserves debating. MATERIALS AND METHODS: A retrospective study including 5654 patients with acute aortic dissection was collected from the National Health Insurance Databases from 1996 to 2001. Age, initial treatment modality, and the late outcome were the main factors to be investigated. Patients are grouped into the young age group when ages are less or equal to 70 and the old age group when over 70. We further subdivided both groups into operative and nonoperative subgroups, respectively, depending on patients receiving surgical intervention for acute aortic dissection or not. The endpoint mortality was defined by the patient death either related to or unrelated to cardiac causes. RESULTS: A total of 5654 cases are with the mean age of 65.6 +/- 14.0 years. The percentage of patients receiving operation was inversely related to the patient's age significantly (p < 0.05). In the old age group, the operative subgroup had both significantly higher survival rate at six-year follow-up than the nonoperative group for both patients on admission and 30-day survivors (43.4 +/- 3.5% vs. 29.8 +/- 2.3%, p < 0.05; 70.0 +/- 4.5% vs. 36.0 +/- 2.8%, p < 0.05). The annual attrition rates of mortality were significantly higher in the nonoperative subgroup for both patients on admission and 30-day survivors (p < 0.05). CONCLUSION: The trend toward more conservative treatment in the elderly still occurs in our common practice even with improving surgical techniques. In our study, we suggest that pertinent surgical strategies for acute aortic dissection are necessary to improve the outcome in elderly patients.
Spatial Coverage Taiwan
Description Country affiliation: Taiwan
Author Affiliation: Wu IH ( Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.)
ISSN 08860440
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2008-03-01
Publisher Place United States
e-ISSN 15408191
Journal Journal of Cardiac Surgery
Volume Number 23
Issue Number 2


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Source: WHO-Global Index Medicus