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Author Tai, Akihiro ♦ Ikeda, Sayoko ♦ Yazama, Futoshi ♦ Ito, Hideyuki
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Elsevier
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Human anatomy, cytology, histology ♦ Human physiology ♦ Pharmacology and therapeutics ♦ Chemical engineering
Subject Domain (in MeSH) Digestive System ♦ Anatomy ♦ Eukaryota ♦ Organisms ♦ Organic Chemicals ♦ Enzymes and Coenzymes ♦ Chemicals and Drugs ♦ Chemical Phenomena ♦ Biological Sciences
Subject Keyword Discipline Biomedical Engineering ♦ Discipline Microbiology ♦ Ascorbic Acid ♦ Chemistry ♦ Metabolism ♦ Esterases ♦ Alpha-glucosidases ♦ Animals ♦ Guinea Pigs ♦ Hydrogen-ion Concentration ♦ Hydrolysis ♦ Intestine, Small ♦ Journal Article
Abstract 2-O- -D-Glucopyranosyl-6-O-(2-pentylheptanoyl)-L-ascorbic acid (6-bDode-AA-2G) underwent an intramolecular acyl migration to yield approximately 12% of 2-O- -D-glucopyranosyl-5-O-(2-pentylheptanoyl)-L-ascorbic acid (5-bDode-AA-2G) in neutral solutions for 3 days. In small intestine homogenate from guinea pigs for 12h, 6-bDode-AA-2G, which hardly underwent acyl migration to give 5-bDode-AA-2G, was predominantly hydrolyzed with -glucosidase and then with esterase to ascorbic acid.
Description Country affiliation: Japan
Author Affiliation: Tai A ( Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Shobara, Hiroshima 727-0023, Japan. atai@pu-hiroshima.ac.jp)
ISSN 13891723
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2012-04-01
Publisher Place Japan
e-ISSN 13474421
Journal Journal of Bioscience and Bioengineering
Volume Number 113
Issue Number 4


Source: WHO-Global Index Medicus