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Author Alloway, Kevin D. ♦ Smith, Jared B. ♦ Beauchemin, Kyle J. ♦ Olson, Michelle L.
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Wiley
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Philosophy & psychology ♦ Psychology ♦ Natural sciences & mathematics ♦ Life sciences; biology ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Human anatomy, cytology, histology ♦ Incidence & prevention of disease ♦ Diseases ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Nervous System ♦ Animal Structures ♦ Anatomy ♦ Eukaryota ♦ Organisms ♦ Diagnosis ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Behavior and Behavior Mechanisms ♦ Psychiatry and Psychology
Subject Keyword Discipline Neurology ♦ Basal Ganglia ♦ Anatomy & Histology ♦ Exploratory Behavior ♦ Physiology ♦ Motor Cortex ♦ Neostriatum ♦ Neural Pathways ♦ Thalamus ♦ Vibrissae ♦ Innervation ♦ Animals ♦ Behavior, Animal ♦ Brain Mapping ♦ Methods ♦ Male ♦ Prosencephalon ♦ Rats ♦ Rats, Sprague-dawley ♦ Journal Article ♦ Research Support, N.i.h., Extramural
Abstract In rats, whisking behavior is characterized by high-frequency synchronous movements and other stereotyped patterns of bilateral coordination that are rarely seen in the bilateral movements of the limbs. This suggests that the motor systems controlling whisker and limb movements must have qualitative or quantitative differences in their interhemispheric connections. To test this hypothesis, anterograde tracing methods were used to characterize the bilateral distribution of projections from the whisker and forepaw regions in the primary motor (MI) cortex. Unilateral tracer injections in the MI whisker or forepaw regions revealed robust projections to the corresponding MI cortical area in the contralateral hemisphere. Both MI regions project bilaterally to the neostriatum, but the corticostriatal projections from the whisker region are denser and more evenly distributed across both hemispheres than those from the MI forepaw region. The MI whisker region projects bilaterally to several nuclei in the thalamus, whereas the MI forepaw region projects almost exclusively to the ipsilateral thalamus. The MI whisker region sends dense projections to the contralateral claustrum, but those to the ipsilateral claustrum are less numerous. By contrast, the MI forepaw region sends few projections to the claustrum of either hemisphere. Bilateral deposits of different tracers in MI revealed overlapping projections to the neostriatum, thalamus, and claustrum when the whisker regions were injected, but not when the forepaw regions were injected. These results suggest that the bilateral coordination of the whiskers depends, in part, on MI projections to the contralateral neostriatum, thalamus, and claustrum.
Description Country affiliation: United States
Author Affiliation: Alloway KD ( Department of Neural & Behavioral Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033-2255, USA. kda1@psu.edu)
ISSN 00219967
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2009-08-10
Publisher Place United States
e-ISSN 10969861
Journal Journal of Comparative Neurology
Volume Number 515
Issue Number 5


Source: WHO-Global Index Medicus