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Author Chakrabarti, Jayprokas ♦ Sahoo, Satyabrata ♦ Mallick, Bibekanand ♦ Das, Smarajit ♦ Ghosh, Zhumur
Source IACS Kolkata
Content type Text
Publisher Indian Association for the Cultivation of Science
File Format PDF
Language English
Subject Domain (in DDC) Natural sciences & mathematics ♦ Physics
Subject Keyword tRNA ♦ Split-tRNA hypothesis ♦ tRNA search program ♦ Nanoarchaeum equitans
Abstract Hidden patterns abound in genome sequences. Sophisticated mathematical algorithms spot them. As of now, several powerful toolsexist for identification of transfer-RNA genes from genomes. These sometimes fail to identify when introns are at noncanonical sites. We discuss ourapproach to this problem of identification and apply it to the genome of Nanoarchaeum equitans. Using our algorithm, we identify the four tRNAgenes that were missed by the present standard tRNA search programs in N. equitans. The recent split-tRNA hypothesis [Nature 433, 537 (2005)]identified the missing ones. However, our solutions are different. We argue the case in favour of our solutions.
Education Level UG and PG
Learning Resource Type Article
Journal Indian J Phys
Volume Number 79
Issue Number 6
Page Count 4
Starting Page 559
Ending Page 562