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Author Henderson, Tara O. ♦ Friedman, Danielle Novetsky
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher MDPI AG
File Format PDF
Date Created 2018-08-07
Copyright Year ©2018
Language English
Subject Domain (in LCC) RJ1-570
Subject Keyword Survivorship ♦ Pediatrics ♦ Neuroblastoma ♦ Medicine ♦ Childhood cancer ♦ Late effects
Abstract Over the past two decades, marked progress has been made in understanding the biology of neuroblastoma; this has led to refined risk stratification and treatment modifications with resultant increasing 5-year survival rates for children with neuroblastoma. Survivors, however, remain at risk for a wide variety of potential treatment-related complications, or “late effects”, which may lead to excess morbidity and premature mortality in this cohort. This review summarizes the existing survivorship literature on long-term health outcomes for survivors of neuroblastoma, focusing specifically on potential injury to the endocrine, sensory, cardiovascular, pulmonary, and renal systems, as well as survivors’ treatment-related risk for subsequent neoplasms and impaired quality of life. Additional work is needed to assess the potential late effects of newer multimodality therapies with the aim of optimizing long-term medical and psychosocial outcomes for all survivors of neuroblastoma.
ISSN 22279067
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2018-08-01
e-ISSN 22279067
Journal Children
Volume Number 5
Issue Number 8
Starting Page 107


Source: Directory of Open Access Journals (DOAJ)