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Author Punter-Villagrasa, Jaime ♦ Cid, Joan ♦ Páez-Avilés, Cristina ♦ Rodríguez-Villarreal, Ivón ♦ Juanola-Feliu, Esteve ♦ Colomer-Farrarons, Jordi ♦ Miribel-Català, Pere Ll
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Multidisciplinary Digital Publishing Institute
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Life sciences; biology ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Diseases ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Eukaryota ♦ Organisms ♦ Hemic and Lymphatic Diseases ♦ Diseases ♦ Diagnosis ♦ Investigative Techniques ♦ Equipment and Supplies ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Natural Science Disciplines ♦ Physical Sciences
Subject Keyword Discipline Biotechnology ♦ Anemia ♦ Biosensing Techniques ♦ Methods ♦ Electric Power Supplies ♦ Hematocrit ♦ Electronics ♦ Humans ♦ Journal Article
Abstract We present a small, compact and portable device for point-of-care instantaneous early detection of anemia. The method used is based on direct hematocrit measurement from whole blood samples by means of impedance analysis. This device consists of a custom electronic instrumentation and a plug-and-play disposable sensor. The designed electronics rely on straightforward standards for low power consumption, resulting in a robust and low consumption device making it completely mobile with a long battery life. Another approach could be powering the system based on other solutions like indoor solar cells, or applying energy-harvesting solutions in order to remove the batteries. The sensing system is based on a disposable low-cost label-free three gold electrode commercial sensor for 50 µL blood samples. The device capability for anemia detection has been validated through 24 blood samples, obtained from four hospitalized patients at Hospital Clínic. As a result, the response, effectiveness and robustness of the portable point-of-care device to detect anemia has been proved with an accuracy error of 2.83% and a mean coefficient of variation of 2.57% without any particular case above 5%.
Description Country affiliation: Spain
Author Affiliation: Punter-Villagrasa J ( Department of Electronics, University of Barcelona, Martí i Franquès 1, Barcelona 08028, Spain. jpunter@el.ub.es.); Cid J ( Department of Hemotherapy and Hemostasis, CDB, IDIBAPS, Hospital Clínic, Villarroel 170, Barcelona 08036, Spain. jcid@clinic.ub.es.); Páez-Avilés C ( Department of Electronics, University of Barcelona, Martí i Franquès 1, Barcelona 08028, Spain. cpaezaviles@el.ub.edu.); Rodríguez-Villarreal I ( Centre de Recerca Matemàtica, Campus Bellaterra, UAB, Edifici C, Barcelona 08193, Spain. irodvill@crm.cat.); Juanola-Feliu E ( Department of Electronics, University of Barcelona, Martí i Franquès 1, Barcelona 08028, Spain. ejuanola@el.ub.edu.); Colomer-Farrarons J ( Department of Electronics, University of Barcelona, Martí i Franquès 1, Barcelona 08028, Spain. jcolomer@el.ub.edu.); Miribel-Català PL ( Department of Electronics, University of Barcelona, Martí i Franquès 1, Barcelona 08028, Spain. pmiribel@el.ub.edu.)
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2015-02-16
Publisher Place Switzerland
e-ISSN 14248220
Journal Sensors
Volume Number 15
Issue Number 2


Source: WHO-Global Index Medicus