Thumbnail
Access Restriction
Open

Author Matsuo, Yukinori
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword APPLIED LIFE SCIENCES ♦ RADIATION PROTECTION AND DOSIMETRY ♦ CALCULATION METHODS ♦ ERRORS ♦ RADIOTHERAPY ♦ RANDOMNESS
Abstract Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.
ISSN 00942405
Educational Use Research
Learning Resource Type Article
Publisher Date 2016-09-15
Publisher Place United States
Journal Medical Physics
Volume Number 43
Issue Number 9


Open content in new tab

   Open content in new tab