|Author||Sansom, B. F.|
|Source||United States Department of Energy Office of Scientific and Technical Information|
|Subject Keyword||BIOLOGY AND MEDICINE ♦ ANIMALS ♦ BLOOD PLASMA ♦ CALCIUM 45 ♦ CALCIUM PHOSPHATES ♦ COWS ♦ DIFFUSION ♦ GOATS ♦ LABELLED COMPOUNDS ♦ PERFORMANCE ♦ PHOSPHORUS 32 ♦ QUANTITY RATIO ♦ RADIOACTIVITY ♦ SKIN ♦ SOLUBILITY ♦ STRONTIUM 89 ♦ STRONTIUM SULFATES ♦ SUSPENSIONS ♦ TESTING ♦ TRACER TECHNIQUES|
|Abstract||A simple method for establishing a constant concentration of a radioactive tracer in the blood plasma for periods of several days or weeks is described. The method consists of the subcutaneous injection of a saline suspension of a sparingly soluble compound labeled with an isotope of the element concerned. This acts as a depot of radioactivity from which slow leaching occurs into the blood stream. In the case of Ca, calcium orthophosphate labeled with / sup 45/Ca was used as the depot, and for phosphorus the same compound labeled with /sup 32/P. Some experiments with Sr were also carried out using strontium sulfate labeled with /sup 45/Sr as the depot, and the princip1e may presumably be extended to other elements of biological interest. (P.C.H.)|
|Learning Resource Type||Article|
|Publisher Department||Argicultural Research Council Inst. for Research on Animal Diseases, Compton, Berks, Eng.|
|Organization||Argicultural Research Council Inst. for Research on Animal Diseases, Compton, Berks, Eng.|
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