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Author Sun, T. ♦ Yin, Y. ♦ Lin, X. ♦ Zhang, G.
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword APPLIED LIFE SCIENCES ♦ RADIATION PROTECTION AND DOSIMETRY ♦ ANIMAL TISSUES ♦ BEAMS ♦ IRRADIATION ♦ LUNGS ♦ MAMMARY GLANDS ♦ MODULATION ♦ NEOPLASMS ♦ OPTIMIZATION ♦ PATIENTS ♦ RADIATION DOSES ♦ RADIATION MONITORS ♦ RADIOTHERAPY ♦ SURGERY
Abstract Purpose: Breast cancer now mainly received forward intensity modulation radiotherapy (f-IMRT) and inverse IMRT (i-IMRT). The purpose of this study was to observe the differences of two treatment methods. Methods: 10 patients after left breast-conserving surgery were selected to receive radiotherapy. For each patient, two treatment plans (f-IMRT and i-IMRT) were designed. For f-IMRT plans, two tangent beams were designed to the target, and in each tangent orientation two or three segment beams were designed to reduced high dose region in the target and the dose of lung received. For i-IMRT plans, two tangent beams were designed to the target and the treatment planning system optimize the dose according to the optimization parameters. For each plan 50Gy was prescribed. Results: In f-IMRT and i-IMRT plans, the average target conformal index (CI) were (0.67±0.06) and (0.66±0.06), (P>0.05); average homogeneity index (HI) were (28.2±6.0)% and (26.1±6.8)%, (P>0.05); volume of left lung received 20Gy (V20) were (18.7±3.3)% and (17.0±2.8)%, (P<0.05), V30 were (15.5±3.0)% and (14.0±2.6)%, (P<0.05); V30 of heart were (4.1±3.1)% and (3.5±2.5)%, (P>0.05); Monitor Unit (MU) were (262±5)MU and (308±14)MU. Conclusion: Compared with i-IMRT plan, for breast cancer, the differences of CI and HI were not significant. Because of fewer MU, f-IMRT plan could reduce the machine abrasion and treatment time, but dose of normal tissue received were higher significantly than i-IMRT plan.
ISSN 00942405
Educational Use Research
Learning Resource Type Article
Publisher Date 2015-06-15
Publisher Place United States
Journal Medical Physics
Volume Number 42
Issue Number 6


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