Thumbnail
Access Restriction
Open

Author Ewen, Lei ♦ Ekim, Jinsook ♦ Eberglund, Ken ♦ Eting, Jonathan T. ♦ Eaugustine, George J. ♦ Edeisseroth, Karl ♦ Ezhang, Xuying ♦ Emancuso, James ♦ Ehira, Riichiro ♦ Ehoffmann, Carolin ♦ Echow, Nicholas ♦ Ematsuzaki, Masanori ♦ Etang, Yanxia ♦ Efeng, Guoping ♦ Ekudolo, John ♦ Equi, Li ♦ Etan, Gregory ♦ Easrican, Brent ♦ Etsuda, Sachiko ♦ Elo, Shunqiang ♦ Egloss, Bernd ♦ Ekasai, Haruo ♦ Echen, Susu ♦ Elee, Liming ♦ Ekatarya, Malvika ♦ Enakajima, Ryuichi ♦ Ezhao, Shengli
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Frontiers Media S.A.
File Format HTM / HTML
Date Created 2014-05-22
Copyright Year ©2013
Language English
Subject Domain (in LCC) RC321-571
Subject Keyword Pons ♦ Neuropsychiatry ♦ Cortex ♦ Biological psychiatry ♦ Neurosciences ♦ Hippocampus ♦ Optogenetics ♦ Internal medicine ♦ Mouse genetics ♦ Medicine ♦ Cerebellum
Abstract Here we characterize several new lines of transgenic mice useful for optogenetic analysis of brain circuit function. These mice express optogenetic probes, such as enhanced halorhodopsin or several different versions of channelrhodopsins, behind various neuron-specific promoters. These mice permit photoinhibition or photostimulation both in vitro and in vivo. Our results also reveal the important influence of fluorescent tags on optogenetic probe expression and function in transgenic mice.
ISSN 16625110
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2013-11-01
e-ISSN 16625110
Journal Frontiers in Neural Circuits
Volume Number 7


Source: Directory of Open Access Journals (DOAJ)