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Researcher Suja, K P
Advisor Dr.Arumughan, C ♦ Dr. Jayalekshmy, A
Source CUSAT-Thesis
Content type Text
Educational Degree Doctor of Philosophy (Ph.D.)
File Format PDF
Language English
Subject Domain (in DDC) Natural sciences & mathematics
Subject Keyword Antioxidants ♦ Sesame ♦ Preamble ♦ Chemical oxidation ♦ Biological oxidation
Abstract In the present study on natural antioxidants, the focus has been keptmainly on oil seeds, especially sesame and its by-products. Sesame, which has beenunder cultivation in India for centuries is called the 'Queen of oil seed crops' because ofthe high yield of oil obtained and the nutritional qualities of the seed, oil, and meal.Though India is the largest producer of sesame in the world, research on the varioushealth benefits of sesame has been carried out by Japanese Sesame has an important placein the foods and tradit..ional medicine of India from time immemorial. Foreseeing thepotential of sesame and its byproducts as an important antioxidant source and itsavailability in bulk, the present study was focussed on Sesamum species. There are notmany reports on the wild species of Sesamum in India, especially of the Kerala region.Hence, in the present study we also included antioxidants of Sesamurnrnalabaricumdistributedthroughout the coastal region.The important characteristics of sesame are attributed to the presence ofthe umquc compounds lignans. Lignans arc a group of natural products of phenyl propanoid ongm, whieh are widely distributed in nature. They display importantphysiological functions in plants, in human nutrition and medicine, given their extensivehealth promotive and curative properties. Much interest has been focussed on theireffectiveness as antineoplastic agents and research in this area has revealed several modesof action by which they can regulate the growth of mammalian cells. Sesame is animportant source of furofuran lignans, of which sesamin and the rare oxygenatedderivative sesamoIin are the most abundant. Others include sesamol and glucosides oflignans. Sesarnin and episesamin are reported to have hypocholesterolemic effect,suppressive effect on chemically induced cancer, alleviation of allergy symptoms etc.Sesamol, sesamolin and the lignan glycosides are reported to inhibit lipid peroxidation.Present investigation on sesame and its byproducts have been carried out to explore thepossibility of developing a natural antioxidant extract from available resources to be usedas a substitute to synthetic ones in vegetable oils and foods. Preliminary analysis showedthat sesame cake, a byproduct could still be utilized as a major source of lignans. Sesamecake, which is now used only as a cattlefeed, can be better utilized in the form of avaluable antioxidant source. The present study explains the development of a feasibleprocess for the extraction of antioxidant compounds from sesame cake. The antioxidantextract so prepared from sesame cake has been tested for vegetable oil protection and isfound to be effective at low concentration. In addition, studies also include theantioxidant, radical scavenging, anticancer, mosquitocidal and pesticidal activities ofextract and individual compounds.
Education Level UG and PG
Learning Resource Type Thesis
Publisher Institution RRL,CSIR