Thumbnail
Access Restriction
Open

Author Tang, S. ♦ Laaroussi, R. ♦ Chen, J. ♦ Samant, P. ♦ Xiang, L. ♦ Chen, Y. ♦ Ahmad, S. ♦ Yang, K.
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword APPLIED LIFE SCIENCES ♦ RADIATION PROTECTION AND DOSIMETRY ♦ ACOUSTICS ♦ ALGORITHMS ♦ ANIMAL TISSUES ♦ BIOMEDICAL RADIOGRAPHY ♦ CHEST ♦ COMPUTERIZED TOMOGRAPHY ♦ IMAGE PROCESSING ♦ IMAGES ♦ MAMMARY GLANDS ♦ NEOPLASMS ♦ PATIENTS ♦ PHANTOMS ♦ RADIATION DOSES ♦ SKELETON ♦ SKIN ♦ SPECIFIC HEAT ♦ THERMAL EXPANSION ♦ ULTRASONIC WAVES
Abstract Purpose: The X-ray induced acoustic computed tomography (XACT) is a new imaging modality which combines X-ray contrast and high ultrasonic resolution in a single modality. Using XACT in breast imaging, a 3D breast volume can be imaged by only one pulsed X-ray radiation, which could dramatically reduce the imaging dose for patients undergoing breast cancer screening and diagnosis. A 3D digital phantom that contains both X-ray properties and acoustic properties of different tissue types is indeed needed for developing and optimizing the XACT system. The purpose of this study is to offer a realistic breast digital phantom as a valuable tool for improving breast XACT imaging techniques and potentially leading to better diagnostic outcomes. Methods: A series of breast CT images along the coronal plane from a patient who has breast calcifications are used as the source images. A HU value based segmentation algorithm is employed to identify breast tissues in five categories, namely the skin tissue, fat tissue, glandular tissue, chest bone and calcifications. For each pixel, the dose related parameters, such as material components and density, and acoustic related parameters, such as frequency-dependent acoustic attenuation coefficient and bandwidth, are assigned based on tissue types. Meanwhile, other parameters which are used in sound propagation, including the sound speed, thermal expansion coefficient, and heat capacity are also assigned to each tissue. Results: A series of 2D tissue type image is acquired first and the 3D digital breast phantom is obtained by using commercial 3D reconstruction software. When giving specific settings including dose depositions and ultrasound center frequency, the X-ray induced initial pressure rise can be calculated accordingly. Conclusion: The proposed 3D breast digital phantom represents a realistic breast anatomic structure and provides a valuable tool for developing and evaluating the system performance for XACT.
ISSN 00942405
Educational Use Research
Learning Resource Type Article
Publisher Date 2016-06-15
Publisher Place United States
Journal Medical Physics
Volume Number 43
Issue Number 6


Open content in new tab

   Open content in new tab