Thumbnail
Access Restriction
Open

Author Rampoldi, Antonio ♦ Barbosa, Fabiane ♦ Secco, Silvia ♦ Migliorisi, Carmelo ♦ Galfano, Antonio ♦ Prestini, Giovanni ♦ Harward, Sardis Honoria ♦ Trapani, Dario Di ♦ Brambillasca, Pietro Maria ♦ Ruggero, Vercelli ♦ Solcia, Marco ♦ Carnevale, Francisco Cesar ♦ Bocciardi, Aldo Massimo
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword RADIOLOGY AND NUCLEAR MEDICINE ♦ ARTERIES ♦ BLADDER ♦ BPH ♦ NEOPLASMS ♦ PATIENTS ♦ PROSTATE ♦ RETENTION ♦ SURGERY ♦ SYMPTOMS ♦ VASCULAR DISEASES
Abstract PurposeTo prospectively assess discontinuation of indwelling bladder catheterization (IBC) and relief of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) following prostate artery embolization (PAE) in poor surgical candidates.MethodsPatients ineligible for surgical intervention were offered PAE after at least 1 month of IBC for management of urinary retention secondary to BPH; exclusion criteria for PAE included eligibility for surgery, active bladder cancer or known prostate cancer. Embolization technical and clinical success were defined as bilateral prostate embolization and removal of IBC, respectively. Patients were followed for at least 6 months and evaluated for International Prostate Symptom Score, quality of life, prostate size and uroflowmetric parameters.ResultsA total of 43 patients were enrolled; bilateral embolization was performed in 33 (76.7%), unilateral embolization was performed in 8 (18.6%), and two patients could not be embolized due to tortuous and atherosclerotic pelvic vasculature (4.7%). Among the patients who were embolized, mean prostate size decreased from 75.6 ± 33.2 to 63.0 ± 23.2 g (sign rank p = 0.0001, mean reduction of 19.6 ± 17.3%), and IBC removal was achieved in 33 patients (80.5%). Clavien II complications were reported in nine patients (21.9%) and included urinary tract infection (three patients, 7.3%) and recurrent acute urinary retention (six patients, 14.6%). Nine patients (22.0%) experienced post-embolization syndrome.ConclusionsPAE is a safe and feasible for the relief of LUTS and IBC in highly comorbid patients without surgical treatment options.
ISSN 01741551
Educational Use Research
Learning Resource Type Article
Publisher Date 2017-04-15
Publisher Place United States
Journal Cardiovascular and Interventional Radiology
Volume Number 40
Issue Number 4


Open content in new tab

   Open content in new tab