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Author Consuelo, López De Padilla ♦ Reed, Ann M.
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher BioMed Central
File Format HTM / HTML
Date Created 2007-08-25
Copyright Year ©2007
Language English
Subject Domain (in LCC) RJ1-570 ♦ RC925-935
Subject Keyword Pediatrics ♦ Internal medicine ♦ Medicine ♦ Diseases of the musculoskeletal system ♦ Specialties of internal medicine
Abstract Abstract Dendritic cells (DCs) are professional antigen-presenting cells that are specialized in the uptake of antigens and their transport from peripheral tissues to the lymphoid organs. Over the last decades, the properties of DCs have been intensely studied and much knowledge has been gained about the role of DCs in various diseases and health conditions where the immune system is involved, particularly in cancer and autoimmune disorders. Emerging clues in autoimmune diseases, suggest that dendritic cell dysregulation might be involved in the development of various autoimmune disorders in both adults and children. However, studies investigating a possible contribution of DCs in autoimmune diseases in the pediatric population alone are scanty. The purpose of this review is to give a general overview of the current literature on the relevance of dendritic cells in the most common autoimmune conditions of childhood.
ISSN 15460096
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2007-07-01
e-ISSN 15460096
Journal Pediatric Rheumatology Online Journal
Volume Number 5
Issue Number 1
Starting Page 16


Source: Directory of Open Access Journals (DOAJ)