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Author Anna, Boguckakocka ♦ Daniel, Zaluski ♦ Danuta, Smolarz Helena
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Sciendo
File Format HTM / HTML
Date Created 2015-09-21
Copyright Year ©2014
Language English
Subject Domain (in LCC) R
Subject Keyword Eleutherosides ♦ Apoptosis ♦ Medicine ♦ Eleutherococcus ♦ Cytotoxicity ♦ HL60
Abstract The Eleutherococcus species including 40 species native to Asia are medicinal plants widely used in traditional medicine. Some of these species are cultivated at the botanical gardens in Europe. On the basis on our earlier studies it was concluded that the extracts of analyzed species act as antioxidants, inhibitors of MMPs, and cytotoxic against Jurkat 45 leukemia cell line. In this study, the anti-leukemic potential of roots and leaves from six Eleutherococcus species cultivated in Poland was determined. The in vitro cytotoxic activity towards human promyelotic leukemia cell line HL60 using trypan blue assay was evaluated. The induction of apoptosis in stimulated leukemia cells was determined by AnnexinV method. Morphological changes in treated cells were observed by microscopic investigations.
ISSN 23006676
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2014-06-01
e-ISSN 23006676
Journal Current Issues in Pharmacy and Medical Sciences
Volume Number 27
Issue Number 1
Page Count 5
Starting Page 41
Ending Page 45

Source: Directory of Open Access Journals (DOAJ)