Thumbnail
Access Restriction
Open

Author Rucinski, A. ♦ Mancini-Terracciano, C. ♦ Paramatti, R. ♦ Pinci, D. ♦ Russomando, A. ♦ Voena, C. ♦ Battistoni, G. ♦ Muraro, S. ♦ Collamati, F. ♦ Faccini, R. ♦ Camillocci, E. Solfaroli ♦ Collini, F. ♦ De Lucia, E. ♦ Piersanti, L. ♦ Toppi, M. ♦ Frallicciardi, P. ♦ Marafini, M. ♦ Patera, V. ♦ Sciubba, A.
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword APPLIED LIFE SCIENCES ♦ RADIATION PROTECTION AND DOSIMETRY ♦ COMPUTER CODES ♦ COMPUTERIZED SIMULATION ♦ HADRONS ♦ ION BEAMS ♦ MEV RANGE 100-1000 ♦ MONITORING ♦ MONITORS ♦ MONTE CARLO METHOD ♦ PARTICLE TRACKS ♦ PERFORMANCE ♦ RADIATION DOSES ♦ RADIOTHERAPY ♦ SPATIAL RESOLUTION
Abstract Purpose: Development of strategies to monitor range uncertainties is necessary to improve treatment planning in Charged Particle Therapy (CPT) and fully exploit the advantages of ion beams. Our group developed (within the framework of the INSIDE project funded by the Italian research ministry) and is currently building a compact detector Dose Profiler (DP) able to backtrack charged secondary particles produced in the patient during the irradiation. Furthermore we are studying monitoring strategy exploiting charged secondary emission profiles to control the range of the ion beam. Methods: This contribution reports on the DP detector design and construction status. The detector consists of a charged secondary tracker composed of scintillating fiber layers and a LYSO calorimeter for particles energy measurement.The detector layout has been optimized using the FLUKA Monte Carlo (MC) simulation software. The simulation of a 220 MeV Carbon beam impinging on a PMMA target has been performed to study the detector response, exploiting previous secondary radiation measurements performed by our group. The emission profile of charged secondary particles was reconstructed backtracking the particles to their generation point to benchmark the DP performances. Results: The DP construction status, including the technological details will be presented. The feasibility of range monitoring with DP will be demonstrated by means of MC studies. The correlation of the charged secondary particles emission shape with the position of the Bragg peak (BP) will be shown, as well as the spatial resolution achievable on the BP position estimation (less than 3 mm) in the clinical like conditions. Conclusion: The simulation studies supported the feasibility of an accurate range monitoring technique exploiting the use of charged secondary fragments emitted during the particle therapy treatment. The DP experimental tests are foreseen in 2016, at CNAO particle therapy center in Pavia.
ISSN 00942405
Educational Use Research
Learning Resource Type Article
Publisher Date 2016-06-15
Publisher Place United States
Journal Medical Physics
Volume Number 43
Issue Number 6


Open content in new tab

   Open content in new tab