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Author Zeliszewska, P. ♦ Adamczyk, Z. ♦ Ciesla, M. ♦ Bratekskicki, A.
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Institute for Condensed Matter Physics
File Format HTM / HTML
Date Created 2016-03-05
Copyright Year ©2016
Language English
Subject Domain (in LCC) QC1-999
Subject Keyword Fibrinogen adsorption ♦ Science ♦ Positively charged microspheres ♦ Physics
Abstract Adsorption of fibrinogen on positively charged microspheres was theoretically and experimentally studied. The structure of monolayers and the maximum coverage were determined by applying the experimental measurements at pH = 3.5 and 9.7 for NaCl concentration in the range of 10^{-3} - 0.15 M. The maximum coverage of fibrinogen on latex particles was precisely determined by the AFM method. Unexpectedly, at pH = 3.5, where both fibrinogen molecule and the latex particles were positively charged, the maximum coverage varied between 0.9 mg m^{-2} and 1.1 mg m^{-2} for 10^{-2} and 0.15 M NaCl, respectively. On the other hand, at pH = 9.7, the maximum coverage of fibrinogen was larger, varying between 1.8 mg m^{-2} and 3.4 mg m^{-2} for 10^{-2} and 0.15 M NaCl, respectively. The experimental results were quantitatively interpreted by the numerical simulations.
ISSN 1607324X
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2016-02-01
e-ISSN 1607324X
Journal Condensed Matter Physics
Volume Number 19
Issue Number 1
Starting Page 13801


Source: Directory of Open Access Journals (DOAJ)